Zyven OD Plus 100 mg/0.5 mg Tablet

Zyven OD Plus 100 mg/0.5 mg Tablet is a combination of two medicines used in the treatment of depression. This medicine helps by increasing the level of chemical messengers in the brain that have a calming effect on the brain and relax the nerves, thus treating your depression.

Zyven OD Plus 100 mg/0.5 mg Tablet may be taken with or without food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include nausea, constipation, confusion, insomnia (difficulty in sleeping), memory impairment, headache, ejaculation disorder, tiredness, erectile dysfunction, low sexual desire, and uncoordinated body movements. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you.

Before taking it, inform your doctor if you are suffering from thyroid or kidney disease, epilepsy, Parkinson's disease, glaucoma, or any heart disease. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. You should avoid alcohol while taking Zyven OD Plus 100 mg/0.5 mg Tablet, as it may worsen certain side effects.

• Treatment of Depression

Treatment of Depression
Zyven OD Plus 100 mg/0.5 mg Tablet helps in maintaining the balance of certain chemicals in the brain that affect mood and behavior. This improves your mood, relieves anxiety, tension, helps you sleep better and increases your energy levels. Zyven OD Plus 100 mg/0.5 mg Tablet prevents extreme changes in mood and helps you feel less agitated. You may experience fewer episodes of depression and low mood.
It can take several weeks for this medicine to work and you may still feel low during this time. It is likely that you will take this medicine for at least six months but possibly much longer. It needs to be taken regularly to work effectively. Do not stop taking it unless your doctor tells you to.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Venew Plus

• Nausea
• Constipation
• Confusion
• Insomnia (difficulty in sleeping)
• Memory impairment
• Headache
• Ejaculation disorder
• Tiredness
• Erectile dysfunction
• Low sexual desire
• Uncoordinated body movements
• Depression

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zyven OD Plus 100 mg/0.5 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Zyven OD Plus 100 mg/0.5 mg Tablet is a combination of two medicines: Desvenlafaxine and Clonazepam. Desvenlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) which works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance. Clonazepam is a benzodiazepine. It works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.

• You have been prescribed Zyven OD Plus 100 mg/0.5 mg Tablet for the treatment of depression.
• Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
• It is also advisable to inform your doctor if you get aggressive, anxiety, trouble sleeping, an increase in activity or talking more than what is normal for you, and other unusual changes in behavior or mood.
• Do not stop taking Zyven OD Plus 100 mg/0.5 mg Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
• Inform your doctor if you are taking any other antidepressants.
• If you have hypertension, monitor your blood pressure regularly while taking Zyven OD Plus 100 mg/0.5 mg Tablet.
• Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
• You have been prescribed Zyven OD Plus 100 mg/0.5 mg Tablet for the treatment of depression.
• Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
• It is also advisable to inform your doctor if you get aggressive, anxiety, trouble sleeping, an increase in activity or talking more than what is normal for you, and other unusual changes in behavior or mood.
• Do not stop taking Zyven OD Plus 100 mg/0.5 mg Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
• Inform your doctor if you are taking any other antidepressants.
• If you have hypertension, monitor your blood pressure regularly while taking Zyven OD Plus 100 mg/0.5 mg Tablet.
• Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.

Desvenlafaxine. Philadelphia, Pennsylvania: Wyeth Pharmaceuticals; 2008 [revised Jul. 2011]. [Accessed 23 Apr. 2019] (online) Available from:

Clonazepam. Boucherville, Québec: Sandoz Canada Inc.; 2018. [Accessed 23 Apr. 2019] (online) Available from:

MedlinePlus. Desvenlafaxine. [Accessed 23 Apr. 2019] (online) Available from:

Clonazepam. Boucherville, Québec: Sandoz Canada Inc.; 2018. [Accessed 23 Apr. 2019] (online) Available from: