Zognis H 150mg/12.5mg Tablet

Zognis H 150mg/12.5mg Tablet is a combination of two medicines. It helps to control high blood pressure in different ways. If high blood pressure is not treated it can lead to heart attacks, strokes and kidney failure.

You can take Zognis H 150mg/12.5mg Tablet with or without food. The dose will depend on your condition and how you respond to the medicine. Try to take it at the same time each day. It is important to keep taking this medicine until your doctor tells you not to. It contains a diuretic (water pill) and will make you urinate more so, it is best to avoid taking this medicine within four hours of going to bed. Use this medicine regularly to get the most benefit from it even if you feel well. High blood pressure does not usually have symptoms and if you stop taking it your risk of heart attack or stroke may increase.

The most common side effect is dizziness. Other side effects include nausea, feeling tired, diarrhea, upset stomach, headache, and decreased blood pressure. Frequent urination is not a side effect of this medicine. It is the purpose of hydrochlorothiazide and helps control your blood pressure. You may experience other possible side effects, but most are rare. Hydrochlorothiazide may occasionally lead to an increase in pressure in your eye and lead to permanent eye damage if not treated. Make sure you read the leaflet that comes with your medicines and tell your doctor if you are bothered by side effects or they do not go away. It may be possible to adjust your dose or try a different medicine.

This medicine is not recommended during pregnancy or while breastfeeding and you should ask your doctor before taking it if you have kidney or liver disease, heart trouble or diabetes. Drinking alcohol can further lower your blood pressure and may cause side effects.

• Hypertension (high blood pressure)

Hypertension (high blood pressure)
Zognis H 150mg/12.5mg Tablet is a combination of two medicines namely Irbesartan and Hydrochlorothiazide. It is generally used when one medicine alone is not controlling your blood pressure effectively. Irbesartan works by relaxing and widening your blood vessels so your blood can flow more easily. This will lower your blood pressure. Hydrochlorothiazide is known as a diuretic (water pill) which increases urine output thereby lowering blood pressure. If your blood pressure is controlled you are less at risk of having a heart attack, stroke, or kidney problems. The medicine must be taken regularly as prescribed to be effective. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zognis H

• Nausea
• Taste change
• Upset stomach
• Diarrhea
• Weakness
• Dizziness
• Headache
• Glucose intolerance
• Increased blood uric acid
• Increased blood lipid level
• Electrolyte imbalance
• Decreased blood pressure

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zognis H 150mg/12.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Zognis H 150mg/12.5mg Tablet is a combination of two medicines: Irbesartan and hydrochlorothiazide which lower blood pressure effectively. Irbesartan is an angiotensin receptor blocker (ARB). It works by blocking the hormone angiotensin thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Hydrochlorothiazide is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.

• You have been prescribed Zognis H 150mg/12.5mg Tablet for the treatment of high blood pressure.

• It can be taken with or without food.

• Zognis H 150mg/12.5mg Tablet may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, very dry mouth or muscle weakness.

• It may cause dizziness. Get up slowly when rising from a sitting or lying position.

• Use of Zognis H 150mg/12.5mg Tablet during pregnancy or breastfeeding is unsafe.

• It may also decrease the risk of stroke and heart attacks.

Hydrochlorothiazide + Irbesartan. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2012 [revised 17 Nov. 2017]. [Accessed 11 Apr. 2019] (online) Available from:

Mayo Clinic. Irbesartan and hydrochlorothiazide. [Accessed 11 Apr. 2019] (online) Available from:

Irbesartan+hydrochlorothiazide. Birżebbuġa, Malta: APL Swift Services (Malta) Limited; 2017. [Accessed 11 Apr. 2019] (online) Avaailable from: