Zione O 20mg/6.25mg Tablet

Zione O 20mg/6.25mg Tablet is a combination of two medicines. It helps to control high blood pressure in different ways. If high blood pressure is not treated it can lead to heart attacks, strokes and kidney failure.

You can take Zione O 20mg/6.25mg Tablet with or without food. The dose will depend on your condition and how you respond to the medicine. Try to take it at the same time each day. It is important to keep taking this medicine until your doctor tells you not to. It contains a diuretic (water pill) and will make you urinate more so, it is best to avoid taking this medicine within four hours of going to bed. Use this medicine regularly to get the most benefit from it even if you feel well. High blood pressure does not usually have symptoms and if you stop taking it your risk of heart attack or stroke may increase.

The most common side effect is dizziness. Other side effects include feeling tired, nausea, diarrhea, headache, and decreased blood pressure. Frequent urination is not a side effect of this medicine. It is the purpose of chlorthalidone and helps control your blood pressure. You may experience other possible side effects, but most are rare. Make sure you read the leaflet that comes with your medicines and tell your doctor if you are bothered by side effects or they do not go away. It may be possible to adjust your dose or try a different medicine.

This medicine is not recommended during pregnancy and you should ask your doctor before taking it if you have kidney or liver disease, heart trouble or diabetes. Drinking alcohol can further lower your blood pressure and may cause side effects.

• Hypertension (high blood pressure)

Hypertension (high blood pressure)
Zione O 20mg/6.25mg Tablet is a combination of two medicines namely Olmesartan and chlorthalidone. It is generally used when one medicine alone is not controlling your blood pressure effectively. Olmesartan works by relaxing and widening your blood vessels so your blood can flow more easily. This will lower your blood pressure. Chlorthalidone is known as a diuretic (water pill) which increases urine output thereby lowering blood pressure. If your blood pressure is controlled you are less at risk of having a heart attack, stroke, or kidney problems. The medicine must be taken regularly as prescribed to be effective. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Olmesar CH

• Nausea
• Taste change
• Diarrhea
• Upset stomach
• Weakness
• Headache
• Dizziness
• Increased blood uric acid
• Increased blood lipid level
• Electrolyte imbalance
• Glucose intolerance
• Decreased blood pressure

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zione O 20mg/6.25mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Zione O 20mg/6.25mg Tablet is a combination of two medicines: Olmesartan and chlorthalidone which lower blood pressure effectively. Olmesartan is an angiotensin receptor blocker (ARB). It works by blocking the hormone angiotensin thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Chlorthalidone is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.

• You have been prescribed Zione O 20mg/6.25mg Tablet for the treatment of high blood pressure.

• It can be taken with or without food.

• Zione O 20mg/6.25mg Tablet may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, very dry mouth or muscle weakness.

• It may cause dizziness. Get up slowly when rising from a sitting or lying position.

• Use of Zione O 20mg/6.25mg Tablet during pregnancy or breastfeeding is unsafe.

• It may also decrease the risk of stroke and heart attacks.

MedIndia. Olmesartan. [Accessed 11 Apr. 2019] (online) Available from:

Olmesartna. Hatfield, Hertfordshire: Generics UK T/A Mylan; 2014 [revised Aug. 2017]. [Accessed 11 Apr. 2019] (online) Available from:

Chlortalidone. Chippenham, Wiltshire: Alliance Pharmaceuticals; 1998 [revised 23 Sep. 2014]. [Accessed 11 Apr. 2019] (online) Available from: