Zetaglim M 3mg/500mg Tablet SR

Zetaglim M 3mg/500mg Tablet SR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.

Zetaglim M 3mg/500mg Tablet SR should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working according to your blood sugar levels.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effect of Zetaglim M 3mg/500mg Tablet SR is low blood glucose levels (hypoglycemia). Make sure you recognize the signs of having low blood glucose levels, such as sweating, dizziness, headache, and shaking, and know how to deal with it. To prevent this, it's important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Other side effects that may be seen on taking this medicine include taste changes, nausea, diarrhea, stomach pain, headache, and upper respiratory tract infection. Some people may find that they put on weight with this medicine.

You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

• Treatment of Type 2 diabetes mellitus

Treatment of Type 2 diabetes mellitus
Zetaglim M 3mg/500mg Tablet SR is a combination medicine that increases the amount of insulin your body produces (in the pancreas). The insulin then works to lower your blood glucose level. It is usually taken once a day. You should keep taking it for as long as it is prescribed.
Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tgmet-G

• Hypoglycemia (low blood glucose level)
• Headache
• Nausea
• Diarrhea
• Flatulence

Take this medicine in the dose and duration as advised by your doctor. Zetaglim M 3mg/500mg Tablet SR is to be taken with food.

Zetaglim M 3mg/500mg Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin.Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

• You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.

• You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Zetaglim M 3mg/500mg Tablet SR.

• Take it with food to lower your chance of having an upset stomach.

• Monitor your blood sugar level regularly while you are taking this medicine.

• It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.

• Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.

• Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Zetaglim M 3mg/500mg Tablet SR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.

• Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Glimepiride + Metformin. Karachi, Pakistan: Sanofi-Aventis Pakistan Ltd. [Accessed 23 Jan. 2019] (online) Available from:

Metformin Hydrochloride Prolonged Release & Glimepiride Tablets I.P. Ankleshwar: Sanofi India Limited; 2018. [Accessed 08 Apr. 2019] (online) Available from:

Glimepiride. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC.; 2009. [Accessed 08 Apr. 2019] (online) Available from:

Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 08 Apr. 2019] (online) Available from:

Glimepiride and Metformin Hydrochloride (in prolonged release form) [Product Monograph]. Ankleshwar, Gujarat: Sanofi India Limited; 2018. [Accessed 28 Oct. 2021] (online) Available from:

American Diabetes Association. 9. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes-2020. Diabetes Care. 2020;43(Suppl 1): S98-S110. [Accessed 28 Oct. 2021] (online) Available from: