Vasolazine Tablet

Vasolazine Tablet is used in the treatment of heart failure. It is a combination of two medicines that effectively control symptoms of heart failure.

Vasolazine Tablet should be taken with food regularly at a fixed time each day. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better. Lifestyle changes like a low-fat diet, exercise, and not smoking may help this medicine to work better.

It is generally safe and suitable for most people but has some potential side effects. The most common side effects of this medicine include nausea, vomiting, diarrhea, and loss of appetite. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It makes you feel dizzy as of orthostatic hypotension (sudden lowering of blood pressure on standing). Hence, rise slowly while from a sitting position or avoid driving. You may be asked for regular monitoring of blood pressure while on the treatment.

Before taking this medicine, tell your doctor if you have liver or kidney disease. You must tell your doctor if you are pregnant, planning pregnancy, or breastfeeding. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.

• Treatment of Heart failure

Treatment of Heart failure
Heart failure means your heart is weak and cannot pump enough blood to your lungs and the rest of your body. The most common symptoms are breathlessness, tiredness, and swelling in your legs, ankles, abdomen and other parts of your body. Vasolazine Tablet makes it easier for your heart to pump blood around your body and is therefore an effective treatment for heart failure.
This medicine will help relieve your symptoms, making you feel better and more energetic. You should make appropriate lifestyle changes, such as eating healthy and keeping active, to help this medicine be effective. Take it regularly and keep taking it even if you feel better.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Muzika

• Headache
• Dizziness

Severe side effects of Muzika

• Enlarged spleen
• Erectile dysfunction
• Paralytic ileus
• Difficulty in urination

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Vasolazine Tablet is to be taken with food.

Vasolazine Tablet is a combination of two medicines: Isosorbide dinitrate and Hydralazine. Isosorbide dinitrate is a nitrate which relaxes the blood vessels and decreases the oxygen demand of the heart. Hydralazine is a potassium channel opener which acts as an antioxidant and lessens tolerance to isosorbide dinitrate, thereby preserving its capacity to relax blood vessels. Together, they improve symptoms of heart failure.

• Vasolazine Tablet is a combination of two medicines that helps improve symptoms of heart failure and keeps your heart healthier.
• This medicine may temporarily cause headaches, especially when starting treatment. Inform your doctor if it does not go away.
• Vasolazine Tablet may cause dizziness. Do not drive or do anything requiring concentration until you know how it affects you.
• To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
• It is best to avoid drinking alcohol while taking Vasolazine Tablet as it may make the side effects worse.
• Do not take it in combination with medicines that treat erectile dysfunction (eg. sildenafil, tadalafil, vardenafil) or high blood pressure, as that can cause a major drop in blood pressure.
• Do not stop taking Vasolazine Tablet suddenly without talking to your doctor as it can increase the risk of heart attack and stroke.

Ferdinand KC, Elkayam U, Mancini D, et al. Use of isosorbide dinitrate and hydralazine in African-Americans with heart failure 9 years after the African-American Heart Failure Trial. Am J Cardiol. 2014;114(1):151-9. [Accessed 21 Jan. 2019] (online) Available from:

Mastanamma SK, Saidulu P, Sravanthi A, et al. Stability Indicating Validated RP-HPLC Method for Simultaneous Determination of Hydralazine Hydrochloride and Isosorbide Dinitrate in Bulk and Pharmaceutical Dosage Form. Int J Pharm Sci Rev Res. 2016;40(1):1411-48. [Accessed 21 Jan. 2019] (online) Available from:

Cheng JW. A review of isosorbide dinitrate and hydralazine in the management of heart failure in black patients, with a focus on a new fixed-dose combination. Clin Ther. 2006;28(5):666-78. [Accessed 21 Jan. 2019] (online) Available from:

Isosorbide dinitrate and hydralazine hydrochloride. Seymour, Indiana: Kremers Urban Pharmaceuticals Inc.; 2005 [revised Apr. 2015]. [Accessed 23 Jan. 2019] (online) Available from: