Trajenta Duo 2.5mg/1000mg Tablet

MRP
₹ 186
PRESCRIPTION REQUIRED
YES
MANUFACTURER/ MARKETER
Boehringer Ingelheim
QUANTITY
10 tablets

Introduction To Trajenta Duo 2.5mg/1000mg Tablet

Trajenta Duo 2.5mg/1000mg Tablet is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage and blindness and may reduce your chance of having a heart attack or stroke.

Trajenta Duo 2.5mg/1000mg Tablet can be prescribed alone or together with other diabetes medications. All diabetes medicines work best when used along with a healthy diet and regular exercise. The dose you are given will depend on your condition, blood sugar levels, and what other medicines you are taking. Taking this medicine with meals helps to reduce the chances of developing an upset stomach.

You should take it regularly, at the same time each day, to get the most benefit. You should not stop this medicine unless your doctor recommends it. It is controlling your blood sugar levels and helping to prevent serious complications in the future. Your lifestyle plays a big part in controlling diabetes. Therefore, it is important to stay on the diet and exercise program recommended by your doctor while taking this medicine.

The most common side effects of taking this medicine include diarrhea, nausea, vomiting, upset stomach, headache, blocked nose (nasal congestion), and sore throat. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin, glimepiride, or sulphonylurea. So you need to know how to recognize and deal with it.

This medicine is not suitable for everyone. Before taking it, you should let your doctor know if you have ever had kidney, liver, or heart disease, problems with your pancreas, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Some other medicines may affect the working of this medicine, so tell your doctor about all the medicines you are taking to make sure you are safe. You should try to avoid drinking alcohol as it lowers blood sugar. Your doctor will check your kidney function and blood sugar levels before and during treatment.

Uses of Trajenta Duo 2.5mg/1000mg Tablet

  • Treatment of Type 2 diabetes mellitus

Benefits of Trajenta Duo 2.5mg/1000mg Tablet

Treatment of Type 2 diabetes mellitus
Trajenta Duo 2.5mg/1000mg Tablet has two active substances in it i.e. metformin and linagliptin. Metformin belongs to a class of medicines called biguanides. Linagliptin belongs to a group called DPP-4 inhibitors. They work together in different ways to lower your blood glucose levels.

Lowering blood glucose levels is an essential part of managing diabetes. If you can control your blood glucose level, your risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs is also lowered. Additionally, proper control of diabetes can also reduce the risk of heart disease and stroke. Taking this medicine regularly along with a proper program of diet and exercise will help you live a normal, healthy life. You should keep using this medicine for as long as it is prescribed because it is protecting your future health.

Side effects of Trajenta Duo 2.5mg/1000mg Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ondero Met

  • Hypoglycemia (low blood glucose level)
  • Nausea
  • Diarrhea
  • Vomiting
  • Flatulence
  • Weight gain

How to use Trajenta Duo 2.5mg/1000mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trajenta Duo 2.5mg/1000mg Tablet is to be taken with food.

How Trajenta Duo 2.5mg/1000mg Tablet works

Trajenta Duo 2.5mg/1000mg Tablet is a combination of two antidiabetic medicines: Metformin and Linagliptin. Metformin is an antidiabetic medication (biguanide). It works by lowering the glucose production in the liver, delaying glucose absorption from the intestines and increasing the body's sensitivity to insulin. Linagliptin is a DPP-4 inhibitor which works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces both fasting and postmeal sugar levels. Together, they provide better control of blood sugar.

Quick tips

  • You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
  • Trajenta Duo 2.5mg/1000mg Tablet should be taken with food to lower the chances of having an upset stomach.
  • Take it in addition to regular exercise and a healthy diet to lower the levels of blood sugar.
  • Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.
  • Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar source with you for immediate relief.
  • Monitor your blood sugar level regularly while you are taking this medicine.
  • Inform your doctor about your diabetes treatment if you are due to have any surgery under a general anesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, or stomach pain as Trajenta Duo 2.5mg/1000mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.

Safety Advice

sdsPregnancyCONSULT YOUR DOCTOR

Can I take Trajenta Duo 2.5mg/1000mg Tablet if I’m pregnant?

Trajenta Duo 2.5mg/1000mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

sdsBreastfeedingUNSAFE

Can I take Trajenta Duo 2.5mg/1000mg Tablet if I’m breastfeeding?

Trajenta Duo 2.5mg/1000mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

sdsAlcoholUNSAFE

Is drinking alcohol while taking Trajenta Duo 2.5mg/1000mg Tablet safe?

It is unsafe to consume alcohol with Trajenta Duo 2.5mg/1000mg Tablet.

sdsDrivingCAUTION

Can I drive after taking Trajenta Duo 2.5mg/1000mg Tablet?

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

sdsKidneyUNSAFE

Can I take Trajenta Duo 2.5mg/1000mg Tablet if I have/had kidney diseases?

Trajenta Duo 2.5mg/1000mg Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.

sdsLiverUNSAFE

Can I take Trajenta Duo 2.5mg/1000mg Tablet if I have/had liver diseases?

Trajenta Duo 2.5mg/1000mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

Frequently Asked Questions

Q. Can the use of Trajenta Duo 2.5mg/1000mg Tablet cause lactic acidosis?

Yes, the use of Trajenta Duo 2.5mg/1000mg Tablet can lead to lactic acidosis which is also known as MALA (Metformin-associated lactic acidosis). It is caused by increased levels of lactic acid in the blood. It is a very rare side effect associated with the use of metformin and therefore it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Trajenta Duo 2.5mg/1000mg Tablet and immediately consult your doctor.

Q. What are the possible side effects of Trajenta Duo 2.5mg/1000mg Tablet?

The use of Trajenta Duo 2.5mg/1000mg Tablet may cause some common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. It can also lead to a serious but rare side effect known as lactic acidosis. Additionally, its long-term use can also lead to vitamin B12 deficiency.

Q. Are there any specific conditions in which Trajenta Duo 2.5mg/1000mg Tablet should not be taken?

The use of Trajenta Duo 2.5mg/1000mg Tablet should be avoided in patients with known allergy to any of the components of this medicine. The use of this medicine should be avoided in patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis. Therefore, consult your doctor before using Trajenta Duo 2.5mg/1000mg Tablet.

Q. Is it safe to take alcohol while I am also taking Trajenta Duo 2.5mg/1000mg Tablet?

No, it is not safe to take Trajenta Duo 2.5mg/1000mg Tablet along with alcohol. Doing so can increase the chances of lactic acidosis, particularly in cases of fasting, malnutrition or kidney dysfunction. However, if you are not sure, consult your doctor.

Q. What are the instructions for the storage and disposal of Trajenta Duo 2.5mg/1000mg Tablet?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Can the use of Trajenta Duo 2.5mg/1000mg Tablet cause hypoglycemia?

The use of Trajenta Duo 2.5mg/1000mg Tablet does not usually cause hypoglycemia (low blood sugar level) on its own. But, it could occur if there is insufficient supplementation of calories while taking this medicine. Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. The symptoms are more likely to be noticed if you miss or delay your food, drink alcohol, over- exercise or take any other antidiabetic medicine along with it. Hence, regular monitoring of blood sugar level is important. It is recommended to always carry glucose tablets, honey or fruit juice with you.

Q. Can the use of Trajenta Duo 2.5mg/1000mg Tablet lead to vitamin B12 deficiency?

Yes, long-term use of Trajenta Duo 2.5mg/1000mg Tablet can cause vitamin B12 deficiency as it interferes with absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems. These may further cause a tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). Consult your doctor if you experience these symptoms. Your doctor may advise monitoring of B12 levels and prescribe a vitamin B12 supplement if required.

References

Written By:

Dr Advikka Ridhy

Dr Advikka Ridhy

MBBS

RMO, Aster MIMS

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