Topilep 100 Tablet
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Introduction To Topilep 100 Tablet
Topilep 100 Tablet is a medicine used to treat epilepsy (seizures) and to prevent migraines. It is also used in the treatment of Lennox-Gastaut syndrome (a rare, but severe form of epilepsy that starts in early childhood).
Topilep 100 Tablet may be taken with or without food, preferably at the same time, each day. If you have missed a dose, take it as soon as you remember it and finish the full course of treatment even if you feel better. Stopping the medication suddenly without talking to your doctor may cause an increased frequency of seizures. Your doctor may advise regular monitoring of serum bicarbonate levels while you are taking this medicine.
Some of the common side effects of this medicine include nausea, taste change, fatigue, diarrhea, weight loss, loss of appetite, and memory impairment. It may also cause vision problems like myopia or glaucoma, so it is important to get your eyesight checked before you start the treatment and regularly thereafter. You may experience dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Please consult your doctor if these side effects bother you or do not go away.
Uses of Topilep 100 Tablet
- Epilepsy/Seizures
- Prevention of Migraine
- Lennox–Gastaut syndrome
Benefits of Topilep 100 Tablet
Epilepsy/Seizures
Topilep 100 Tablet is an anticonvulsant (or anti-epileptic) medicine that works by
decreasing the nerve impulses which cause the seizures. By controlling the
frequency of seizures, it will help you go about your daily activities with
more confidence. It helps reduce symptoms such as confusion, uncontrollable
jerking movements, loss of awareness, and fear or anxiety.
This medicine is not associated with any physical or psychological dependence
(addiction) but it should not be stopped suddenly. It must be taken regularly
as prescribed to be effective. Missing doses may trigger a seizure.
Prevention of Migraine
It is not fully established how Topilep 100 Tablet helps prevent migraines. It may
change the abnormal and excessive activity of the nerve cells in the brain or
increase the activity in a region of the brain associated with migraines. By
preventing and reducing the frequency of headaches, it can help you carry out
your daily activities and have a better quality of life.
Lennox–Gastaut syndrome
Lennox-Gastaut syndrome (LGS) is a rare but severe form of epilepsy that
usually starts in early childhood. Affected children may experience several
different types of seizures. Topilep 100 Tablet helps prevent and control these
seizures by decreasing the nerve impulses which cause the seizures.
Side effects of Topilep 100 Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Topcnx
- Abdominal pain
- Diarrhea
- Dizziness
- Fatigue
- Fever
- Loss of appetite
- Memory impairment
- Nausea
- Nervousness
- Numbness
- Psychomotor impairment
- Sleepiness
- Speech disorder
- Taste change
- Upper respiratory tract infection
- Visual impairment
- Weight loss
How to use Topilep 100 Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Topilep 100 Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Topilep 100 Tablet works
Topilep 100 Tablet is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.
Quick tips
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Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
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Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
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Some healthy tips to prevent seizures:
- Practice yoga every day.
- Get enough sleep at nighttime.
- Limit the use of screen time such as mobile/laptop.
- Take your medication on time.
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It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
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Keep yourself hydrated by drinking plenty of fluids throughout the day while taking Topilep 100 Tablet. This can reduce the risk of kidney stones.
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Monitor your weight during treatment with this medicine as it can cause weight gain.
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Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
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Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
Safety Advice
PregnancyCONSULT YOUR DOCTOR
Can I take Topilep 100 Tablet if I’m pregnant?
Topilep 100 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
BreastfeedingCONSULT YOUR DOCTOR
Can I take Topilep 100 Tablet if I’m breastfeeding?
Topilep 100 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
AlcoholUNSAFE
Is drinking alcohol while taking Topilep 100 Tablet safe?
It is unsafe to consume alcohol with Topilep 100 Tablet.
DrivingUNSAFE
Can I drive after taking Topilep 100 Tablet?
Topilep 100 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
KidneyCAUTION
Can I take Topilep 100 Tablet if I have/had kidney diseases?
Topilep 100 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Topilep 100 Tablet may be needed. Please consult your doctor.
LiverCAUTION
Can I take Topilep 100 Tablet if I have/had liver diseases?
Topilep 100 Tablet should be used with caution in patients with liver disease. Dose adjustment of Topilep 100 Tablet may be needed. Please consult your doctor.
Frequently Asked Questions
Q. For how long do I need to take Topilep 100 Tablet?
The dose and duration of this medicine will depend on your doctor’s advice. Topilep 100 Tablet does not cure your condition (seizures/migraine) but prevents them from occurring. So, you may have to keep taking it for months or years depending on improvement in your symptoms and side effects that may occur.
Q. Is Topilep 100 Tablet good for anxiety?
Topilep 100 Tablet is not indicated for the treatment of anxiety. Please consult your doctor before taking the medicine.
Q. What are the serious side effects of Topilep 100 Tablet?
Serious side effects of Topilep 100 Tablet are rare. The serious effects of Topilep 100 Tablet may include glaucoma (difficulty in seeing, eye pain, and blurred vision), kidney stones (sharp pain in your sides or lower back), and metabolic acidosis (tiredness, loss of appetite, irregular and faint heartbeat). Other serious side effects of Topilep 100 Tablet could be suicidal thoughts and insufficient sweating (some children taking Topilep 100 Tablet may not sweat enough in hot weather, causing their body temperatures to rise).
Q. I am taking valproic acid for fits. Will Topilep 100 Tablet interfere with the working of valproic acid?
Can this combination be taken? Topilep 100 Tablet does not interfere with the working of valproic acid, but it increases the risk of getting excess levels of ammonia in the blood (hyperammonemia). Increased levels of ammonia in the blood can be dangerous and may cause difficulty in thinking, remembering information, or solving problems. It may also decrease your alertness and make you feel very sleepy with low energy. Immediately inform your doctor if you notice these symptoms. It is important to know that, in rare cases, Topilep 100 Tablet alone can cause hyperammonemia.
Q. Can Topilep 100 Tablet be used in children?
Yes, Topilep 100 Tablet is used for seizures in children more than 2 years of age. However, because of the lack of any reports, this medicine is not recommended to be used in children for migraines. Q. Since I have started using Topilep 100 Tablet people are saying that I have lost weight. Is it because of Topilep 100 Tablet or something else for which I should get investigated? It could be due to Topilep 100 Tablet because Topilep 100 Tablet commonly causes weight loss probably due to a decrease in appetite. If you still have any doubts, talk to your doctor who will advise you appropriately.
References
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Written By:
Dr Advikka Ridhy
MBBS
RMO, Aster MIMS
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