Toframine 5 mg/25 mg Tablet

Toframine 5 mg/25 mg Tablet is a prescription medicine used in the treatment of depression. It is a combination medicine that calms the brain by relaxing the nerve cells. It also increases the level of chemical messengers in the brain that help in regulating mood.

Toframine 5 mg/25 mg Tablet can be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as it has habit-forming potential. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medication suddenly without talking to your doctor as this can cause withdrawal effects like depression and difficulty sleeping.

Some common side effects of this medicine include constipation, difficulty in urination, weight gain, confusion, orthostatic hypotension (sudden lowering of blood pressure on standing). This medicine may cause weight loss. In case of losing weight, consult a dietitian for dietary supplements or try to increase your food portion. Most of the common side effects tend to be mild. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects are rare. Remember to inform your doctor if you develop any unusual changes in mood as it may lead to suicidal thoughts.

Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

• Depression

Depression
Toframine 5 mg/25 mg Tablet helps in maintaining the balance of certain chemicals in the brain that affect mood and behavior. This improves your mood, relieves anxiety, tension, helps you sleep better and increases your energy levels. Toframine 5 mg/25 mg Tablet also prevents extreme changes in mood and helps you feel less agitated. You may experience fewer episodes of depression and low mood.
It can take several weeks for this medicine to work and you may still feel low during this time. It is likely that you will take this medicine for at least six months but possibly much longer. It needs to be taken regularly to work effectively. Do not stop taking it unless your doctor tells you to.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sanmin

• Constipation
• Difficulty in urination
• Weight gain
• Confusion
• Orthostatic hypotension (sudden lowering of blood pressure on standing)
• Tiredness
• Blurred vision
• Dryness in mouth
• Increased heart rate
• Uncoordinated body movements
• Depression
• Memory impairment

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Toframine 5 mg/25 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Toframine 5 mg/25 mg Tablet is a combination of two medicines: Diazepam and imipramine which treat depression. Diazepam is a benzodiazepine (BZD) which works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain. Imipramine is a tricyclic antidepressant which increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

• You have been prescribed Toframine 5 mg/25 mg Tablet for the treatment of depression.
• Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
• It is also advisable to inform your doctor if you get aggressive, anxiety, trouble sleeping, an increase in activity or talking more than what is normal for you, and other unusual changes in behavior or mood.
• Do not stop taking Toframine 5 mg/25 mg Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
• Inform your doctor if you are taking any other antidepressants.
• If you have hypertension, monitor your blood pressure regularly while taking Toframine 5 mg/25 mg Tablet.
• Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.

Diazepam. South San Francisco, California: Genentech USA Inc.; 2013. [Accessed 22 Apr. 2019] (online) Available from:

Drugs.com. Imipramine. [Accessed 23 Apr. 2019] (online) Available from:

Drugs.com. Diazepam. [Accessed 22 Apr. 2019] (online) Available from:

Medscape. Imipramine. [Accessed 23 Apr. 2019] (online) Available from: