Synodox 2mg/500mg/10mg Tablet
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Introduction To Synodox 2mg/500mg/10mg Tablet
Synodox 2mg/500mg/10mg Tablet is a combination medicine for treating the common cold, fever, and flu symptoms. It contains chlorpheniramine maleate (which lowers allergic reactions), paracetamol (which lowers pain and fever), and phenylephrine (which reduces nasal congestion). They relieve symptoms such as runny or stuffy nose, sneezing, watery eyes, and itchy throat. Your doctor may prescribe this medication for the common cold, hay fever/rhinitis, seasonal allergies, and flu.
Synodox 2mg/500mg/10mg Tablet should be taken as advised by your doctor. The dosage may be adjusted depending on your pain level. You can take it before or after eating. To prevent adverse effects, take it as per your doctor’s prescription.
Side effects of Synodox 2mg/500mg/10mg Tablet can include drowsiness, headache, nausea, loss of appetite, constipation, vomiting, and dry mouth. They usually don't last long and often go away by themselves. If they continue, talk to your doctor.
Synodox 2mg/500mg/10mg Tablet is contraindicated (unsafe) for people who are lactating and hypersensitive to chlorpheniramine maleate, paracetamol, or phenylephrine. Always inform your doctor of medical conditions like heart and liver disease. Generally, this combination drug is considered safe for most people.
How Synodox 2mg/500mg/10mg Tablet works
Synodox 2mg/500mg/10mg Tablet contains three ingredients: chlorpheniramine maleate (allergy medication), paracetamol (pain and fever medication), and phenylephrine (nasal decongestant). They relieve symptoms such as sore throat, headache, runny nose, muscular pain, and fever.
Phenylephrine, the first ingredient in Synodox 2mg/500mg/10mg Tablet, is a synthetic direct-acting adrenergic agonist. It acts on adrenergic receptors that affect the contraction of blood vessels. When we take this medicine, these receptors are activated, resulting in the shrinkage of dilated/swollen blood vessels. This effect inside the sinus and nasal cavity reduces nasal congestion and relieves symptoms like a stuffy nose.
Paracetamol, also known as acetaminophen, is the second ingredient in this combination. It is an analgesic (treats pain) and an antipyretic (treats fever) agent. It works by targeting cyclooxygenase-mediated prostaglandin synthesis in the brain.
Synodox 2mg/500mg/10mg Tablet also contains chlorpheniramine maleate, an H1-receptor antagonist. It is an antihistamine that works against chemicals called histamines. This chemical is responsible for most of the allergic responses, such as coughing, sneezing, vomiting, and runny nose, which are means of getting rid of allergens from the body.
People with severe allergies experience these symptoms due to the exaggerated function of these histamines. The histamines work by binding with the H1 receptors in our body. That is why chlorpheniramine maleate is prescribed for people with the cold and flu; it competitively inhibits the interaction of histamine with its H1 receptors, ridding patients of their allergic symptoms.
Dosage
Take Synodox 2mg/500mg/10mg Tablet as prescribed by your doctor. Never consume more than the prescribed daily dose. Swallow the tablet as a whole with a glass of water; do not chew or crush it. You can take this medicine before or after your meals. Taking it at night before bed is recommended since it may make you sleepy.
Your doctor might prescribe two tablets per day depending on the symptoms. For nasal stuffiness, the typical adult dosage of phenylephrine is 10 mg taken orally every 4 hours, with a maximum allowable dose of 60 mg within 24 hours. The maximum single dose of paracetamol is 1000 mg, with a maximum daily dose of 4 grams. Chlorpheniramine maleate should not exceed 24 mg per day.
If you forget to take this medication, take it as soon as you remember. If it is time for your next dose, ignore the one that you missed and continue with the next. To compensate for a missed dose, avoid taking twice the amount.
Taking more than the prescribed dose of this anti-allergic medicine may lead to side effects like dizziness and sleepiness worsening since Chlorpheniramine Maleate, contained in Synodox 2mg/500mg/10mg Tablet, is a mild sedative.
Do not take this medicine longer than the prescribed duration. Overusing medications containing nasal decongestants like phenylephrine can cause rebound congestion - your nasal congestion worsens because of extended use.
Safety Advice
Synodox 2mg/500mg/10mg Tablet is unsafe for people with liver or kidney disease, cardiovascular diseases, and allergies to chlorpheniramine maleate, paracetamol, and phenylephrine. Always let your doctor know of your detailed medical history. Generally, this medicine is considered safe for most people.
Do not consume more than the prescribed dose since it may result in excessive drowsiness. Extended use after your prescribed duration can result in rebound nasal congestion, making you partially dependent on the medicine. Taking excess amounts in a short period can cause acetaminophen intoxication, which results in kidney and liver damage
PregnancyConsult doctor
Can I take Synodox 2mg/500mg/10mg Tablet if I’m pregnant?
BreastfeedingConsult doctor
Can I take Synodox 2mg/500mg/10mg Tablet if I’m breastfeeding?
AlcoholUnsafe
Is drinking alcohol while taking Synodox 2mg/500mg/10mg Tablet safe?
DrivingUnsafe
Can I drive after taking Synodox 2mg/500mg/10mg Tablet?
KidneyCaution
Can I take Synodox 2mg/500mg/10mg Tablet if I have/had kidney diseases?
LiverCaution
Can I take Synodox 2mg/500mg/10mg Tablet if I have/had liver diseases?
Drug interactions
Drug-Food interaction
As this medication contains a mild sedative, it is not recommended to consume alcohol while taking this medicine. The common side effects, like drowsiness or dizziness, might be worsened.
Drug-Disease interaction
Synodox 2mg/500mg/10mg Tablet is contraindicated if you are hypersensitive to chlorpheniramine maleate, paracetamol, and phenylephrine. Exercise caution while taking this medicine if you have kidney or liver diseases, asthma, enlarged prostate gland, adrenal gland problems, chronic bronchitis, heart diseases or high blood pressure, narrow-angle glaucoma, peptic ulcer, benign prostatic hyperplasia or hyperthyroidism (overactive thyroid).
Drug-Drug interaction
Consult your doctor if you are currently taking the following medicines: Blood thinners (warfarin, heparin), hypoglycemic drugs (metformin), blood pressure-lowering medicines (methyldopa, guanethidine, nebivolol), cough suppressants (dextromethorphan), antidepressant medications (desipramine, tranylcypromine, isocarboxazid), medicines for asthma (albuterol), stomach acidity reducing drugs (pantoprazole)
Drug-Drug Interactions Checker List:
Warfarin Heparin Metformin Methyldopa Guanethidine Nebivolol Dextromethorphan Desipramine Tranylcypromine Isocarboxazid Albuterol Pantoprazole
Frequently Asked Questions
Q. Will Synodox 2mg/500mg/10mg Tablet make me feel sleepy/drowsy?
Yes, sleepiness is a common side effect. Synodox 2mg/500mg/10mg Tablet is a medicine containing Chlorpheniramine Maleate, a mild sedative, so you might feel drowsy after taking it.
Q. What is Synodox 2mg/500mg/10mg Tablet used for?
Synodox 2mg/500mg/10mg Tablet is used to treat the common cold and flu symptoms. It contains chlorpheniramine maleate (which lowers allergic reactions), paracetamol (which lowers pain and fever), and phenylephrine (which reduces nasal congestion).
Q. What are the side effects of Synodox 2mg/500mg/10mg Tablet?
Synodox 2mg/500mg/10mg Tablet may cause drowsiness, headache, nausea, loss of appetite, constipation, vomiting, and dry mouth. They usually don't last long; talk to your doctor if they persist for long.
Q. How long does it take for Synodox 2mg/500mg/10mg Tablet to work?
Synodox 2mg/500mg/10mg Tablet the onset of action is 1-3 hours; your allergic symptoms and breathing difficulty will reduce within the first hour of use. The effect of this medicine lasts 24 hours.
References
Substitutes:
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Written By:
Dr Advikka Ridhy
MBBS
RMO, Aster MIMS
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