Stable 500mg Injection

Stable 500mg Injection is a natural female sex hormone, progesterone. It is used to treat menstrual and pregnancy-related issues that are caused due to hormonal imbalance.

Stable 500mg Injection is also prescribed along with estrogen as a part of hormonal replacement therapy for preventing endometrial hyperplasia (thickening of the lining of the uterus). It should be taken without food, preferably in the evening or at bedtime. It should be taken at the same time each day to get the most benefit. You should continue taking it for as long as your doctor has told you to, even if you feel well.

The most common side effects include abdominal bloating, abdominal pain, dizziness, headache, depression, breast tenderness, hot flushes, vaginal discharge, joint paint, and urinary incontinence. Side effects are more common during the first few weeks and usually lessen as your body gets used to the medicine. You may also experience bleeding or spotting between your periods, consult with your doctor if it happens frequently. If you experience dizziness or tiredness, avoid driving or activity which requires mental concentration.

Before taking this medicine, inform your doctor if you have, or have had, breast cancer, unusual bleeding in the vagina, or liver disease. You will probably have several tests both before and during treatment to check your womb. Also, tell your doctor what other medicines you are taking as some may affect, or be affected by, this medicine.

• Hormone replacement therapy
• Female infertility

Hormone replacement therapy
Hormone Placement Therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.

Female infertility
Stable 500mg Injection contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. Progesterone helps to prepare the uterus for pregnancy by causing the uterus lining (endometrium) to thicken. This increases the chance of a successful pregnancy. You should use the medicine as prescribed for it to be effective. You may be asked to continue with this treatment for a period after becoming pregnant.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of NT Natal MP

• Abdominal bloating
• Hot flushes
• Vaginal discharge
• Urinary incontinence
• Headache
• Fatigue
• Joint pain
• Cough
• Abnormal menstrual bleeding
• Musculoskeletal (bone, muscle or joint) pain
• Slurred speech
• Pain behind eyes
• Vertigo

Severe side effects of NT Natal MP

• Nausea
• Sleepiness
• Abdominal pain
• Absence of menstrual periods
• Itching
• Change in body weight
• Breast tenderness
• Depression
• Abnormal vaginal bleeding
• Menstrual disorder
• Edema (swelling)
• Changes in cervical ectropion
• Changes in cervical secretion
• Cholestatic jaundice
• Nipple discharge
• Injection site reactions (pain, swelling, redness)
• Red spots or bumps
• Acne
• Hair loss
• Excessive hair growth on face
• Anaphylactic reaction
• Fever
• Insomnia (difficulty in sleeping)

Take this medicine in the dose and duration as advised by your doctor. Stable 500mg Injection is to be taken empty stomach.

Stable 500mg Injection is a progesterone (female hormone). It works on the lining of the uterus and helps to establish and maintain pregnancy in infertile women. It helps in protecting the uterus from the negative effects of oestrogen when used for the treatment of postmenopausal symptoms.

• Stable 500mg Injection is used in the treatment of female infertility and as a part of hormone replacement therapy.
• It regulates menstrual cycles, treats heavy bleeding, and prevents thickening of the uterus.
• It is also used to restore menstruation in women with secondary amenorrhea (the absence of menstrual cycles).
• It should be taken without food, preferably in the evening or at bedtime.
• It may cause sleepiness or drowsiness. Don't drive or do anything that requires mental focus until you know how Stable 500mg Injection affects you.
• It may cause bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently.

Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 706-707.

Levin ER, Hammes SR. Estrogens and Progestins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1180-85.

Mayo Clinic. Progesterone. [Accessed 03 Apr. 2019] (online) Available from:

Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:

Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from: