Speridon Plus Tablet

Speridon Plus Tablet is a combination medicine used in the treatment of schizophrenia. It works by modulating the action of certain chemical messengers in the brain that affect thoughts.

Speridon Plus Tablet is taken with or without food, preferably at night. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. It is important not to stop this medicine suddenly without talking to the doctor as it may worsen your symptoms.

Some common side effects of this medicine include nausea, constipation, and dryness in mouth. Initially, this medicine may cause a sudden drop in the blood pressure when you change positions, so it is better to rise slowly if you have been sitting or lying down. It also causes dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may increase your weight, blood sugar, and cholesterol but modifying your lifestyle by having a healthy diet and exercising regularly can reduce this side effect.

Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

• Schizophrenia

Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Speridon Plus Tablet helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life. Do not stop taking it unless advised by the doctor. It can take several weeks for your symptoms to improve; so keep using the medicine even if you do not think it is working.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ristab LS

• Nausea
• Constipation
• Dryness in mouth
• Weight gain
• Sleepiness
• Orthostatic hypotension (sudden lowering of blood pressure on standing)
• Increased prolactin level in blood
• Nervousness

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Speridon Plus Tablet may be taken with or without food, but it is better to take it at a fixed time.

Speridon Plus Tablet is a combination of two medicines: Risperidone and Trihexyphenidyl. Risperidone is an atypical antipsychotic which works by balancing the levels of chemical messengers (dopamine and serotonin) to improve mood, thoughts, and behavior. Trihexyphenidyl is an anticholinergic which works on the nervous system and corrects some of the chemical imbalances that cause Parkinson's disease and certain side effects occurring during antipsychotic treatment.

• Speridon Plus Tablet is a combination medicine that helps treat schizophrenia or mania.
• Trihexyphenidyl controls drug induced abnormal movements.
• Use caution while driving or doing anything that requires concentration as Speridon Plus Tablet can cause dizziness and sleepiness.
• Avoid consuming alcohol while taking this medication as it may lower its efficacy.
• It can cause dry mouth. Maintain good oral hygiene,drink water, chew sugarless gum, or suck on hard candy for the dry mouth.
• It may cause an increase in weight, blood sugar, cholesterol, and triglycerides (fat). Eat healthy, exercise, and monitor your levels regularly.
• Inform your doctor if you have glaucoma or trouble passing urine.
• Do not stop taking Speridon Plus Tablet without talking to your doctor first as it may cause worsening of symptoms.

Risperidone. High Wycombe, Bucks: Janssen-Cilag Ltd.; 2000 [revised Sep. 2018]. [Accessed 22 Apr. 2019] (online) Available from:

Drugs.com. Trihexyphenidyl. [Accessed 22 Apr. 2019] (online) Available from:

Risperidone. County Cork, Ireland: Janssen Pharmaceutical; 1993. [Accessed 22 Apr. 2019] (online) Available from:

Trihexyphnidyl. Huddersfield, West Yorkshire: Genus Pharmaceuticals; 2011 [revised 18 Dec. 2018]. [Accessed 22 Apr. 2019] (online) Available from: