Seroflo 250 Synchrobreathe

Seroflo 250 Synchrobreathe is a combination of two medicines that opens the airways and makes it easier to breathe. It is used in the treatment of asthma (wheezing and shortness of breath) and chronic obstructive pulmonary disorder (a lung disorder in which the flow of air to the lungs is blocked).

Your doctor will tell you how often you need to use your inhaler. The effect of this medicine may be noticeable after a few days but will only reach its maximum after a few weeks. This medicine must be used regularly to be effective, so go on taking it even if you don't have any symptoms. That means it's doing its job. If you stop taking it your asthma and chronic obstructive pulmonary disorder (COPD) may get worse. It should not be used to relieve sudden asthma attacks. If an asthma attack occurs, use your quick-relief inhaler (reliever). To get the benefit from this medicine you need to make sure you get your inhaler technique right, otherwise, it does not work as well.

The most common side effects are nausea, vomiting, respiratory tract infection, fungal infections in the mouth, headache, hoarseness of voice, sore throat, cough, musculoskeletal (bone, muscle, or joint) pain, and increased heart rate. If you get there, do not stop taking it but do talk to your doctor. You can help prevent some of these symptoms by rinsing your mouth and throat with water or brushing your teeth after using your inhaler. There are other, rarer side effects that can be serious. Talk to your doctor if you're worried about them. In general, you should be trying to avoid situations that make your asthma worse (your triggers) and try not to smoke.

Ask your doctor whether it's safe to take this medicine if you're pregnant or breastfeeding. Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.

• Treatment of Chronic obstructive pulmonary disease (COPD)

Treatment of Chronic obstructive pulmonary disease (COPD)
Seroflo 250 Synchrobreathe helps the airways in your lungs stay open. It relaxes the muscles of these airways. This makes it easier for air to get in and out. It will relieve symptoms such as tightness in your chest, shortness of breath, wheezing and coughing and help you carry out your daily activities more easily. This medicine is safe and effective. It usually starts to work within a few minutes and the effects can last up to several hours. Do not stop using it unless you are advised to by your doctor.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Seroflo

• Headache
• Cough
• Upper respiratory tract infection
• Nasopharyngitis (inflammation of the throat and nasal passages)
• Sinus inflammation
• Stomach discomfort
• Fungal infection of oropharynx
• Tremors
• Palpitations
• Voice change

Rotacaps must not be swallowed. Check the label for directions before use. Place the capsule at the base of rotahaler, not in the mouthpiece. Twist the mouthpiece completely until your hear a click and breathe in deeply through the mouthpiece. Hold your breath for up to 10 seconds. If some powder remains in the rotahaler repeat the process.

Seroflo 250 Synchrobreathe is a combination of two medicines: Salmeterol and Fluticasone Propionate. Salmeterol is a long-acting bronchodilator which works by relaxing the muscles in the airways and widens the airways. Fluticasone Propionate is a steroid. It works by stopping the release of certain chemical messengers that cause inflammation (swelling) of the airways. Together, they make breathing easier.

• This medicine is for inhalation only. The tablet should not be swallowed.
• It should be taken at the same time each day.
• It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing.
• Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
• Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.
• Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.
• Your doctor may regularly monitor your blood potassium level as low oxygen level in the blood (hypoxia) and medicines such as Seroflo 250 Synchrobreathe can lower blood potassium level.
• Only miniscule amounts of Seroflo 250 Synchrobreathe may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.

Mayo Clinic. Fluticasone And Salmeterol (Inhalation Route). [Accessed 18 Apr. 2019] (online) Available from:

MedlinePlus. Fluticasone and Salmeterol Oral Inhalation. [Accessed 18 Apr. 2019] (online) Available from:

Fluticasone propionate/formoterol fumarate dihydrate. Cambridge, UK: Bard Pharmaceuticals Limited; 2018. [Accessed 24 Apr. 2019] (online) Available from: