Rostryp 25mg Tablet

Rostryp 25mg Tablet is a tricyclic antidepressant that is used to treat depression and nighttime bedwetting (nocturnal enuresis). Additionally, it may also be prescribed for neuropathic pain.

Rostryp 25mg Tablet works by increasing the levels of chemical messengers in the brain that stabilizes and enhances the mood. It is better to take it before bedtime because it can make you feel drowsy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms.

The most common side effects of this medicine include increased heart rate, blurred vision, dryness in the mouth, difficulty in urination, and constipation. Initially, this medicine may also cause a sudden drop in blood pressure when you change positions. It may even cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. To lower the chance of dizziness, rise slowly if you have been sitting or lying down. It may also lead to weight gain in some people. Most of the common side effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects associated with this medicine are rare.

Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same or any other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. This medicine is not known to be addictive, but you can experience additional side effects (withdrawal symptoms) if you stop taking it suddenly. If you notice any sudden mood change or get suicidal or self-harm thoughts, you must consult the doctor without delay. Also, remember to take this medicine strictly as advised by the doctor as an overdose of this medication may lead to a serious health emergency. Consumption of alcohol should be avoided as alcohol interacts with this medicine to cause serious health issues.

• Depression
• Bed-wetting
• Neuropathic pain

Depression
Rostryp 25mg Tablet works by increasing the level of a chemical called serotonin in the brain. This improves your mood, relieves anxiety, tension, and helps you sleep better. It has fewer side effects than older antidepressants. It usually takes a few weeks for this medicine to work so you need to keep taking it even if you feel it is not working. Do not stop taking it, even if you feel better unless your doctor advises you to.

Bed-wetting
Bed-wetting is a condition that is seen in children who are old enough to control their urine at night during sleep but fail to do so. Rostryp 25mg Tablet can help your child control nighttime bed-wetting. Rostryp 25mg Tablet works by blocking the effect of a certain natural substance (acetylcholine) on the bladder muscles. This prevents bladder overflow at night. However, this medicine is used for managing bed-wetting only during the night.

Neuropathic pain
Rostryp 25mg Tablet is used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles, or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It is thought to work by interfering with pain signals that travel through the damaged nerves and the brain. Taking this medicine regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to take it regularly even if you feel it is not doing any good. Once your symptoms have gone you should still keep taking the medicine until your doctor advises you to stop.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Noraus

• Increased heart rate
• Weight gain
• Difficulty in urination
• Orthostatic hypotension (sudden lowering of blood pressure on standing)
• Dryness in mouth
• Constipation
• Blurred vision

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rostryp 25mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Rostryp 25mg Tablet is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

• Rostryp 25mg Tablet is used for the treatment of depression and bedwetting in children.
• The main dose should be taken at night as this drug may cause drowsiness or sleepiness.
• You may be asked for regular blood tests to monitor the blood cell count or level of sodium and sugar in the blood.
• Inform your doctor if you notice behavioral changes, mood changes and suicidal thoughts while taking this medicine.
• Do not drive or do anything that requires concentration until you know how the medicine affects you.
• Do not stop taking the medication suddenly without talking to your doctor.

Stahl SM, editor. Nortriptyline. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 477-83.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1006-1007.

Nortriptyline hydrochloride [EMC SmPC]. Ballybofey, County Donegal: Pharmaceuticals Ltd.; 2010 [revised 22 Feb. 2019]. [Accessed 25 Mar. 2019] (online) Available from:

Drugs.com. Nortriptyline Pregnancy and Breastfeeding Warnings. [Accessed 06 Mar. 2020] (online) Available from:

Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 25 Mar. 2019] (online) Available from: