Retisphere 0.05% Cream

Retisphere 0.05% Cream is a form of vitamin A that is used to treat acne which appears as spots or pimples on your face, chest, or back. It also helps to smooth rough facial skin and to reduce fine wrinkles on the skin.

Retisphere 0.05% Cream reduces excessive oil production of the skin. Ideally, a pinpoint application at nighttime is recommended for the duration prescribed by your doctor. The amount you need and for how long you need to take it will depend on what you are being treated for. You should normally wash and dry the affected area before applying a thin layer of this medicine. Follow your doctor's instructions. You should not apply it to damaged or broken skin and avoid contact with your mouth, eyes, and nose. It may take several weeks for your symptoms to improve but keep using it regularly to get the most benefit. Consult your doctor again if you do not notice any improvement after a few weeks. Using more medicine or applying it more often than prescribed will not make it work any faster and may increase the side effects.

The most common side effects include irritation, dryness, and redness of the skin. They are usually mild and improve as your body gets used to the medicine. Drink plenty of water and use moisturizer as it may lead to dryness of the mouth, lips, and eyes. Let your doctor know if these side effects bother you or do not go away. Serious side effects with this medicine are rare.

This medicine may make you more sensitive to sunlight so you should limit exposure to the sun if possible. It may make your skin more fragile. It is advised, not to have any waxing (hair removal), or laser treatments during treatment. Pregnant women or women who are planning to get pregnant should not use this medicine as it can lead to birth defects.

• Treatment of Acne
• Acute promyelocytic leukaemia

Treatment of Acne
Retisphere 0.05% Cream is a form of vitamin A. It helps treat acne by clearing skin pores and preventing spots or pimples from appearing. It usually takes several weeks to have a noticeable effect so keep using it even if it appears not to be working. Sometimes acne may get worse before it gets better, however, with proper use, your skin will get clearer. The earlier you start using it, the less likely you are to get scars. This medicine will help improve your mood and uplift your confidence as your skin becomes acne-free. It should not be used if you have eczema or sunburned skin.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Acnerus T

• Erythema (skin redness)
• Skin irritation
• Dry skin
• Dry lips
• Pale red skin
• Increased sensitivity to light

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

Retisphere 0.05% Cream is a form of vitamin A. When applied on the skin, it reduces oil production in the skin, replenishes acne-prone skin, and helps keep your pores open.

• You have been prescribed Retisphere 0.05% Cream for the treatment of acne.
• Clean the affected area with water and a non-medicated soap. Let it dry for 20-30 minutes before applying Retisphere 0.05% Cream.
• It may increase the severity of the spots or pimples in the first few weeks of use. Continue using it as prescribed by your doctor.
• It may cause a stinging sensation or a feeling of warmth when you first start using it. Inform your doctor if this persists.
• Avoid exposure to sunlight while using Retisphere 0.05% Cream as it increases the sensitivity of your skin. Use protective measures such as sunscreen or protective clothing.
• Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile.
• Avoid taking tetracycline (e.g. doxycycline) as it may reduce the Retisphere 0.05% Cream activity.
• Do not use Retisphere 0.05% Cream if you are pregnant.
• Inform your doctor if excessive skin dryness or skin sensitivity takes place.
• Do not use Retisphere 0.05% Cream if you are pregnant.
• Inform your doctor if excessive skin dryness or skin sensitivity takes place.

Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1810.

Sardana K, Madan A. How to Treat Acne. Sardana K, editor. In: Clinical Approach to Acne Vulgaris. 1st ed. New Delhi: CBS Publishers & Distributors Pvt. Ltd.; 2015. pp. 35-36.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1395-98.

Tretinoin. Manati, Puerto Rico: Janssen Ortho LLC; 1997 [revised Jan. 2014]. [Accessed 03 Apr. 2019] (online) Available from:

Drugs.com. Tretinoin Topical Pregnancy and Breastfeeding Warnings. [Accessed 03 Apr. 2019] (online) Available from:

Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from: