Progiron 100 Soft Gelatin Capsule

Progiron 100 Soft Gelatin Capsule is a natural female sex hormone, progesterone. It is used to treat menstrual and pregnancy-related issues that are caused due to hormonal imbalance.

Progiron 100 Soft Gelatin Capsule is also prescribed along with estrogen as a part of hormonal replacement therapy for preventing endometrial hyperplasia (thickening of the lining of the uterus). It should be taken with food. It should be taken at the same time each day to get the most benefit. You should continue taking it for as long as your doctor has told you to, even if you feel well.

The most common side effects include abdominal bloating, abdominal pain, dizziness, headache, depression, breast tenderness, hot flushes, vaginal discharge, joint paint, and urinary incontinence. Side effects are more common during the first few weeks and usually lessen as your body gets used to the medicine. You may also experience bleeding or spotting between your periods, consult with your doctor if it happens frequently.

Before taking this medicine, inform your doctor if you have, or have had, breast cancer, unusual bleeding in the vagina, or liver disease. You will probably have several tests both before and during treatment to check your womb. Also, tell your doctor what other medicines you are taking as some may affect, or be affected by, this medicine. In general, it is advisable to avoid alcohol and smoking.

• Hormone replacement therapy
• Treatment of Female infertility

Hormone replacement therapy
Hormone placement therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness, and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. Progesterone is one of two important hormones (the other being is estrogen) used in this treatment. However, it may not treat all your symptoms, consult with your doctor. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.

Treatment of Female infertility
Progiron 100 Soft Gelatin Capsule contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. This medicine helps to prepare the uterus for pregnancy by causing the uterus lining (endometrium) to thicken. This increases the chance of a successful pregnancy. You should use the medicine as prescribed for it to be effective. You may be asked to continue with this treatment for a period after becoming pregnant.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sonagest

• Hot flushes

Severe side effects of Sonagest

• Abdominal pain
• Sleepiness
• Absence of menstrual periods
• Itching
• Flatulence
• Nausea
• Depression
• Breast tenderness
• Abnormal vaginal bleeding
• Altered menstrual cycle
• Edema (swelling)
• Change in body weight
• Changes in cervical secretion
• Cholestatic jaundice
• Injection site reactions (pain, swelling, redness)
• Red spots or bumps
• Acne
• Hair loss
• Excessive hair growth on face
• Anaphylactic reaction
• Fever
• Insomnia (difficulty in sleeping)
• Soreness
• Diarrhea
• Vaginal irritation
• Vaginal dryness
• Dementia
• Deep vein thrombosis (blood clot in the legs)
• Myocardial infarction
• Stroke
• Pulmonary embolism
• Breast cancer

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Progiron 100 Soft Gelatin Capsule is to be taken with food.

Progiron 100 Soft Gelatin Capsule is a progesterone (female hormone). It helps to establish and maintain pregnancy. It also prevents the increase in thickness of the endometrium (lining of the uterus) caused by estrogen.

• Progiron 100 Soft Gelatin Capsule is a natural progesterone available as a micronized formulation which helps in better absorption of this medicine.
• It is used as a part of hormone replacement therapy generally in combination with an estrogen.
• It may also be used in the treatment of problems related to menstrual periods such as amenorrhea (absence of periods).
• It also helps in the maintenance of pregnancy in women who are at higher risk of miscarriage.
• It should be taken with food.
• It may cause sleepiness or drowsiness. If this happens to you, do not drive or use machinery.

Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 706-707.

Medscape. Progesterone (Natural Micronized). [Accessed 03 Apr. 2019] (online) Available from:

[Progesterone. London, UK: Besins Healthcare (UK) Ltd.; 2003 [revised 14 Jul. 2017]. Accessed 22 Jan. 2019. (online) Available from:

Apgar S, Greenberg G. Using Progestins in Clinical Practice. Am Fam Physician. 2000;62(8):1839-46. [Accessed 03 Apr. 2019] (online) Available from: