Prepit Capsule

Prepit Capsule is a prescription medicine used in the treatment of nausea or vomiting experienced as a side effect of chemotherapy or anti-cancer treatment. It inhibits the signal to reach the brain that causes the feeling of nausea or vomiting.

Prepit Capsule is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are constipation, indigestion, headache, tiredness, loss of appetite, and hiccups. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine can cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness. Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding.

• Nausea and vomiting due to chemotherapy

Nausea and vomiting due to chemotherapy
Prepit Capsule blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused due to some medicines or cancer treatment. This medicine helps you recover more comfortably from cancer treatments such as radiation therapy or chemotherapy. It is also effective at preventing nausea and vomiting after an operation (in adults only). Take it as prescribed by the doctor to get maximum benefit.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Aprifast

• Constipation
• Indigestion
• Headache
• Tiredness
• Loss of appetite
• Hiccup
• Increased liver enzymes

Take this medicine in the dose and duration as advised by your doctor. Prepit Capsule may be taken with or without food, but it is better to take it at a fixed time.

Prepit Capsule is a combination of two different doses of Aprepitant. It works by blocking the action of a chemical messenger in the brain that may cause nausea and vomiting during treatment with anti-cancer medicines.

• Prepit Capsule is taken alongside other medicines to help stop sickness (nausea and vomiting) after chemotherapy.
• Even if you do not feel like eating or drinking, try to sip water regularly to prevent you from becoming lacking in fluid in the body (dehydrated).
• If you are taking any contraceptive 'pill' at the same time as this medicine, the effectiveness of the 'pill' can be reduced if you have a bout of being sick (vomiting) which lasts for more than 24 hours. In such a case, ask your doctor for additional contraceptive precautions.

Aprepitant. Haarlem, The Netherlands: Merck Sharp & Dohme B.V.; 2018. [Accessed 15 Apr. 2019] (online) Available from:

Aprepitant. Whitehouse Station, New Jersey: Merch & Co, Inc.; 2006. [Accessed 15 Apr. 2019] (online) Available from: