Pirozem DT Tablet
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Introduction To Pirozem DT Tablet
Pirozem DT Tablet is a pain-relieving medicine. It is used in the treatment of moderate to severe pain. It helps to relieve pain and swelling of various conditions related to joints and muscles. It is usually given in cases where oral administration is unsuitable.
Pirozem DT Tablet is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep receiving the medicine until the doctor says it is okay to stop using the medicine.
The most common side effects of this medicine include injection site reactions (such as pain, redness, and swelling), vomiting, stomach pain, indigestion, diarrhea, headache, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
This medicine is not recommended for pregnant or breastfeeding women. Pregnant and breastfeeding mothers must consult with their doctors before using the medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
Uses of Pirozem DT Tablet
- Pain relief
Benefits of Pirozem DT Tablet
Pain relief
Pirozem DT Tablet is used for short-term relief of pain, inflammation, and swelling
in conditions that affect joints and muscles. It works by blocking chemical
messengers in the brain that tell us we have pain. It can help relieve pain in
conditions like rheumatoid arthritis and osteoarthritis or even after a dental
(tooth-related) surgery.
Take it as it is prescribed to get the most benefit. Do not take more or for
longer than needed as that can be dangerous. In general, you should take the
lowest dose that works, for the shortest possible time. This will help you to
go about your daily activities more easily and have a better, more active,
quality of life.
Side effects of Pirozem DT Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dracam
- Injection site reactions (pain, swelling, redness)
- Vomiting
- Stomach pain
- Nausea
- Headache
- Dizziness
How to use Pirozem DT Tablet
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Pirozem DT Tablet works
Pirozem DT Tablet is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).
Quick tips
- Pirozem DT Tablet helps relieve pain and swelling of various joints and muscles.
- It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
- Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Safety Advice
PregnancyCONSULT YOUR DOCTOR
Can I take Pirozem DT Tablet if I’m pregnant?
Pirozem DT Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
BreastfeedingSAFE IF PRESCRIBED
Can I take Pirozem DT Tablet if I’m breastfeeding?
Pirozem DT Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
AlcoholCAUTION
Is drinking alcohol while taking Pirozem DT Tablet safe?
Caution is advised when consuming alcohol with Pirozem DT Tablet. Please consult your doctor.
DrivingUNSAFE
Can I drive after taking Pirozem DT Tablet?
Pirozem DT Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
KidneyCAUTION
Can I take Pirozem DT Tablet if I have/had kidney diseases?
Pirozem DT Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Pirozem DT Tablet may be needed. Please consult your doctor. No dose adjustment is recommended in patients with mild to moderate kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine.
LiverCAUTION
Can I take Pirozem DT Tablet if I have/had liver diseases?
Pirozem DT Tablet should be used with caution in patients with liver disease. Dose adjustment of Pirozem DT Tablet may be needed. Please consult your doctor.
Frequently Asked Questions
Q. What is the difference between Pirozem DT Tablet and diclofenac?
Both Pirozem DT Tablet and diclofenac are pain killers. However, piroxicam is a non- selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Pirozem DT Tablet.
Q. What is the difference between Pirozem DT Tablet and naproxen?
Both Pirozem DT Tablet and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Pirozem DT Tablet.
Q. What is the difference between Pirozem DT Tablet and meloxicam?
Both Pirozem DT Tablet and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Pirozem DT Tablet.
Q. What is the difference between Pirozem DT Tablet and ketoprofen?
Both Pirozem DT Tablet and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Pirozem DT Tablet. Ketoprofen gel also showed excellent tolerability.
Q. What is the difference between Pirozem DT Tablet and tramadol?
Pirozem DT Tablet is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
Q. What is the difference between Pirozem DT Tablet and nimesulide?
Both Pirozem DT Tablet and nimesulide are pain killers. However, Pirozem DT Tablet is a non- selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Q. Can Pirozem DT Tablet be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Pirozem DT Tablet or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Pirozem DT Tablet.
Q. Are Pirozem DT Tablet and aspirin same?
No. Pirozem DT Tablet and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti- inflammatory and analgesic.
Q. Can Pirozem DT Tablet be used along with dexamethasone?
No. Pirozem DT Tablet should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Q. Can Pirozem DT Tablet be used with methocarbamol?
Yes. Methocarbamol can be used with Pirozem DT Tablet as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Can Pirozem DT Tablet be used along with paracetamol?
Yes. Paracetamol can be used with Pirozem DT Tablet as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Is Pirozem DT Tablet a NSAID?
Yes. Pirozem DT Tablet is a non-steroidal anti-inflammatory drug (NSAID).
Q. Is Pirozem DT Tablet a sulfa drug?
Pirozem DT Tablet is a sulphur containing compound. Pirozem DT Tablet can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Q. Is Pirozem DT Tablet a blood thinner?
No. Pirozem DT Tablet is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
Q. Is Pirozem DT Tablet a muscle relaxant?
No. Pirozem DT Tablet is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Q. Is Pirozem DT Tablet a narcotic?
No. Pirozem DT Tablet is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
Q. Can Pirozem DT Tablet be used in hypertension?
No. Pirozem DT Tablet is not a medication to control hypertension. It is important to note that Pirozem DT Tablet decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Pirozem DT Tablet.
Q. Can Pirozem DT Tablet be used along with Losartan?
No. Pirozem DT Tablet should not be combined with Losartan. It is important to note that Pirozem DT Tablet decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Pirozem DT Tablet.
Q. Can Pirozem DT Tablet be used with Lisinopril?
No. Pirozem DT Tablet should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Pirozem DT Tablet.
Q. Can Pirozem DT Tablet be used with calcium channel blocker?
Yes. Pirozem DT Tablet can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Q. Can Pirozem DT Tablet be used with Tizanidine?
Yes, Pirozem DT Tablet can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Q. Why is beta cyclodextrin added to Pirozem DT Tablet?
Yes. Pirozem DT Tablet can be combined with beta-cyclodextrin. Research has shown that combining Pirozem DT Tablet with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
Q. Are there any alternatives of Pirozem DT Tablet?
Yes. There are alternatives to Pirozem DT Tablet. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
Q. What are the contraindications for Pirozem DT Tablet?
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
Q. Can Pirozem DT Tablet be used in the treatment of allergy?
No. Pirozem DT Tablet is not a drug to treat allergy. It is a pain killer.
Q. How long does Pirozem DT Tablet work?
Pirozem DT Tablet is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Q. Can you get high by using Pirozem DT Tablet?
No. Pirozem DT Tablet is not known to cause high. It is a non-narcotic painkiller.
Q. Can Pirozem DT Tablet be used to treat menstrual cramp?
Pirozem DT Tablet is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
Q. Can I use Pirozem DT Tablet for a migraine?
Pirozem DT Tablet is not approved for the treatment of migraine. Research studies have shown that Pirozem DT Tablet is effective in significantly decreasing the pain associated with migraine without aura.
Q. Is Pirozem DT Tablet effective in back pain management?
Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Pirozem DT Tablet as the cause of back pain can be different for different person.
Q. Is Pirozem DT Tablet affective in gout management?
Yes. Pirozem DT Tablet can be given for the treatment of acute gout. Research studies have shown Pirozem DT Tablet to be highly effective in the treatment of acute gout.
Q. Can you donate blood when on the medication with Pirozem DT Tablet?
Yes. You can donate blood when on Pirozem DT Tablet. Do inform your doctor before donating blood.
Q. Can I use Pirozem DT Tablet if I am a diabetic?
Pirozem DT Tablet in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Pirozem DT Tablet so taking piroxicam can lead to increased risk of renal failure by many folds.
Q. Can I use Pirozem DT Tablet if I have a deranged renal function?
No. Pirozem DT Tablet should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Q. Can Pirozem DT Tablet lead to skin reactions?
Yes. Pirozem DT Tablet is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
Q. Can I use Pirozem DT Tablet if I am pregnant?
No. Pirozem DT Tablet should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Q. Can I use Pirozem DT Tablet if I have peptic ulcer disease?
No. Pirozem DT Tablet is contraindicated in cases of active peptic ulcer disease. Pirozem DT Tablet is known to cause gastric ulceration and bleeding.
Q. Can I use Pirozem DT Tablet if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti- inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Q. Can Pirozem DT Tablet lead to difficulty in conception?
Yes. Pirozem DT Tablet can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Q. Can Pirozem DT Tablet be used with diuretics?
No. Pirozem DT Tablet should not be used with diuretics. Pirozem DT Tablet reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Q. Can Pirozem DT Tablet be used with lithium?
No. Pirozem DT Tablet should not be used with lithium. Pirozem DT Tablet leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Q. Can Pirozem DT Tablet be used with warfarin?
No. Pirozem DT Tablet should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
Q. What increases the chances of getting a gastric ulcer when I am already taking Pirozem DT Tablet?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Q. Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Pirozem DT Tablet?
Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
Q. What are the serious side effects of Pirozem DT Tablet?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
References
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Written By:
Dr Advikka Ridhy
MBBS
RMO, Aster MIMS
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