Pacinac NP 250mg/10mg Tablet
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Introduction To Pacinac NP 250mg/10mg Tablet
Pacinac NP 250mg/10mg Tablet is a combination of domperidone and naproxen prescribed to treat migraine attacks (acute management of migraines). This medication works by blocking certain pain-causing chemical substances and preventing the stimulation of the brain's vomiting centre. It reduces symptoms like nausea, vomiting and headaches.
Pacinac NP 250mg/10mg Tablet should be taken as advised by your doctor. The dose of the medication may be adjusted depending on the severity of your symptoms. It is best to take this medicine with your meal to prevent stomach upset. To avoid adverse effects, take it as per your doctor’s prescription.
The common side effects of Pacinac NP 250mg/10mg Tablet include dry mouth, dizziness, cold symptoms, ringing in ears, headache and flatulence (gas). They typically last for a short period and should not be of any concern. Contact your healthcare provider if they persist or worsen.
Pacinac NP 250mg/10mg Tablet might be contraindicated (unsafe) for people with vertigo, peptic and gastric ulcers, kidney impairment, severe liver disease, congestive heart failure or allergies to either domperidone or naproxen. Always let your doctor know of any health conditions you might have. This combination drug is generally considered safe for most people.
Uses of Pacinac NP 250mg/10mg Tablet
Pacinac NP 250mg/10mg Tablet is used for the acute management of migraines as it treats migraine attacks (severe headaches with nausea, vomiting and sensitivity to light). This medication works by blocking pain-causing chemical substances and preventing the stimulation of the brain's vomiting centre. This medication may also be prescribed for various medical conditions that cause pain, nausea, and vomiting.
Pacinac NP 250mg/10mg Tablet comprises two active medicines: domperidone and naproxen. Domperidone is an anti-sickness medication that treats vestibular disorders, vomiting and nausea. Naproxen is a nonsteroidal anti-inflammatory drug that relieves pain.
How Pacinac NP 250mg/10mg Tablet works
Pacinac NP 250mg/10mg Tablet contains domperidone and naproxen; it works by blocking certain enzymes and preventing the stimulation of the brain's vomiting centre. It reduces symptoms like nausea, vomiting and pain associated with migraine headaches.
Domperidone can be classed as an anti-sickness medication. It belongs to a group of drugs named dopamine-2 receptor antagonists. This inhibition of dopamine receptors in our body allows it to act as a prokinetic (medicines that increase the speed of food passage in the digestive system) and an antiemetic agent (medicines that reduce nausea and vomiting).
Naproxen is a non-steroidal anti-inflammatory drug that reduces pain and inflammation. It works by inhibiting enzymes called COX-1 and COX-2. This lowers the synthesis of prostaglandins (hormone-like chemicals responsible for pain and inflammation). Its analgesic properties are attributed to its ability to lower levels of prostaglandin in the tissue and blood.
Dosage
Always take Pacinac NP 250mg/10mg Tablet as prescribed by your doctor. Never consume more than the prescribed dose. Swallow it whole with plenty of water. You can take this medicine with your meals (to prevent an upset stomach) or as your doctor recommends.
If you forget to take this medicine, take it as soon as you remember. If it is time for your next dose, ignore the one that you missed and continue with the next. Do not take twice the amount to compensate for a missed dose.
Cases of overdosing are rare but possible. Speak to your doctor about any allergies you might have to the ingredients of this medicine. If you experience signs like blood in urine, difficulty breathing, severe abdominal pain and fast or irregular heart rate, seek medical attention immediately.
Safety Advice
Pacinac NP 250mg/10mg Tablet might be contraindicated (unsafe) for people with vertigo, peptic and gastric ulcers, kidney impairment, liver disease, congestive heart failure or allergies to either domperidone or naproxen. Let your doctor know of any health conditions you might have.
PregnancyCaution
Can I take Pacinac NP 250mg/10mg Tablet if I’m pregnant?
BreastfeedingConsult doctor
Can I take Pacinac NP 250mg/10mg Tablet if I’m breastfeeding?
AlcoholCaution
Is drinking alcohol while taking Pacinac NP 250mg/10mg Tablet safe?
DrivingUnsafe
Can I drive after taking Pacinac NP 250mg/10mg Tablet?
Drug interactions
Drug-Food interaction
Consumption of alcohol while taking Pacinac NP 250mg/10mg Tablet is not recommended because it may worsen stomach acid-related symptoms like heartburn and ulcers.
Drug-Disease interaction
Pacinac NP 250mg/10mg Tablet might be contraindicated (unsafe) for people with vertigo, peptic and gastric ulcers, kidney impairment, liver disease, congestive heart failure or allergies to either domperidone or naproxen.
Drug-Drug interaction
Please consult your doctor if you are currently taking the following medicines: medicines for HIV (atazanavir, nelfinavir), antibiotics (amikacin, ciprofloxacin, clarithromycin), neurokinin-1 receptor antagonist (aprepitant), antacids (aluminium hydroxide), antiarrhythmic medications (amiodarone), beta-blocker medicines (bisoprolol) and cholesterol-lowering drugs (atorvastatin).
Drug-Drug Interactions Checker List:
Atazanavir Nelfinavir Amikacin Ciprofloxacin Clarithromycin Aprepitant aluminium hydroxide Amiodarone Bisoprolol Atorvastatin
Frequently Asked Questions
Q. What is Pacinac NP 250mg/10mg Tablet’s content?
Pacinac NP 250mg/10mg Tablet contains domperidone (anti-sickness medicine) and naproxen (pain-relieving medicine). It is usually prescribed for the acute management of migraines.
Q. What is the Pacinac NP 250mg/10mg Tablet used for?
Pacinac NP 250mg/10mg Tablet treats and prevents migraine attacks (severe headaches with throbbing pain, nausea, vomiting and sensitivity to light).
Q. What are the side effects of Pacinac NP 250mg/10mg Tablet?
The common side effects of Pacinac NP 250mg/10mg Tablet include dry mouth, dizziness, cold symptoms, ringing in ears, headache, and flatulence (gas).
Q. Is Pacinac NP 250mg/10mg Tablet a steroid?
No, Pacinac NP 250mg/10mg Tablet is not a steroid. It comprises a non-steroidal pain reliever called naproxen and an anti-sickness medicine named domperidone.
Q. Does Pacinac NP 250mg/10mg Tablet cause sleep?
Yes, Pacinac NP 250mg/10mg Tablet may cause sleepiness along with dizziness and lightheadedness as side effects. Contact your doctor if they worsen or persist for long.
References
Substitutes:
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Vomigra 250mg/10mg Tablet
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Written By:
Dr Advikka Ridhy
MBBS
RMO, Aster MIMS
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