Pabreca 125mg Capsule

MRP
₹ 7600
PRESCRIPTION REQUIRED
YES
MANUFACTURER/ MARKETER
Lupin Ltd
QUANTITY
21 capsules
SALT COMPOSITION
Palbociclib (125mg)

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Introduction To Pabreca 125mg Capsule

Pabreca 125mg Capsule is used to treat patients with certain types of breast cancer (estrogen receptor-positive, human epidermal growth factor receptor 2-negative) which have spread to other organs. It is given together with hormonal anticancer therapies.

Pabreca 125mg Capsule should be taken with food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Some common side effects of this medicine include fatigue, hair loss, rash, vomiting, and diarrhea. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. It is better to inform your doctor if you notice symptoms of infection like fever, chills, and weakness, bleeding or bruising and nose bleed. It might also cause dizziness if it happens avoid driving or attention-seeking activities.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Pabreca 125mg Capsule

  • Breast cancer

Benefits of Pabreca 125mg Capsule

Breast cancer
Pabreca 125mg Capsule helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Pabreca 125mg Capsule kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.

Side effects of Pabreca 125mg Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Palbinas

  • Decreased blood cells (red cells, white cells, and platelets)
  • Fatigue
  • Hair loss
  • Rash
  • Vomiting
  • Diarrhea
  • Nausea
  • Decreased appetite
  • Infection
  • Decreased white blood cell count
  • Stomatitis (Inflammation of the mouth)
  • Anemia (low number of red blood cells)
  • Weakness
  • Fever

How to use Pabreca 125mg Capsule

Take this medicine in the dose and duration as advised by your doctor. Pabreca 125mg Capsule is to be taken with food.

How Pabreca 125mg Capsule works

Pabreca 125mg Capsule is an anti-cancer medication. Cyclin dependent kinase 4 and 6 (chemical messengers) are downstream of signaling pathways which lead to the proliferation of cells. This medicine works by inhibiting cyclin dependent kinase 4 and 6, thus arrests the cancer cell cycle (cell growing process). It also targets the estrogen (hormone) receptor-positive breast cancer cells by disrupting the cell cycle.

Quick tips

  • Take it with food, preferably at the same time every day.
  • If you forget to take the medicine or vomit, skip the missed dose and follow a regular schedule. Do not take a double dose to make up missed dose
  • Use effective contraception method to prevent pregnancy while taking this medicine.
  • It may cause dizziness. Avoid driving or any activity requiring mental focus until you know how it affects you.
  • You may be asked for regular blood tests while taking this medication. Inform your doctor if you notice symptoms of infection like fever, chills, and weakness.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
  • Do not stop taking the medication without talking to your doctor first.

Safety Advice

sdsPregnancyCONSULT YOUR DOCTOR

Can I take Pabreca 125mg Capsule if I’m pregnant?

Pabreca 125mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

sdsBreastfeedingUNSAFE

Can I take Pabreca 125mg Capsule if I’m breastfeeding?

Pabreca 125mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

sdsAlcoholCONSULT YOUR DOCTOR

Is drinking alcohol while taking Pabreca 125mg Capsule safe?

It is not known whether it is safe to consume alcohol with Pabreca 125mg Capsule. Please consult your doctor.

sdsDrivingUNSAFE

Can I drive after taking Pabreca 125mg Capsule?

Pabreca 125mg Capsule may cause side effects which could affect your ability to drive. It may cause fatigue in some people. If this happens, you should exercise caution when driving or using machines.

sdsKidneySAFE IF PRESCRIBED

Can I take Pabreca 125mg Capsule if I have/had kidney diseases?

Pabreca 125mg Capsule is safe to use in patients with kidney disease. No dose adjustment of Pabreca 125mg Capsule is recommended.

sdsLiverCAUTION

Can I take Pabreca 125mg Capsule if I have/had liver diseases?

Pabreca 125mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Pabreca 125mg Capsule may be needed. Please consult your doctor.

Frequently Asked Questions

Q. What kind of medicine is Pabreca 125mg Capsule?

Pabreca 125mg Capsule is an anti-cancer medicine. Pabreca 125mg Capsule blocks proteins known as cyclin-dependent kinase inhibitors. Blocking these proteins can slow down the growth of cancer cells and delay the progression of the cancer.

Q. How long do I have to take Pabreca 125mg Capsule?

The duration of treatment varies from person to person. Your doctor will decide the number of cycles you need to receive based on your condition, response to treatment and your tolerance to side effects. Your doctor may decrease your dose or stop your treatment temporarily or permanently if you experience certain side effects.

Q. Are the side effects of Pabreca 125mg Capsule irreversible?

No, most of the side effects are reversible and disappear when the medicine is stopped. Neutropenia is a well-recognized adverse effect of Pabreca 125mg Capsule in which the number of your white blood cells get reduced and your immune system gets weakened. As a result, you may be at greater risk of getting an infection while you are taking Pabreca 125mg Capsule. However, this side effect disappears rapidly once you stop taking the medicine.

Q. Does treatment with Pabreca 125mg Capsule require monitoring of blood counts?

Yes, blood tests are important since this medicine can lower your blood counts. The regular blood tests check the effect of Pabreca 125mg Capsule on your blood cells (white blood cells, red blood cells, and platelets). These tests should be done at the beginning of each chemotherapy cycle, on the 15th day of the first 2 cycles, and as clinically indicated.

Q. How should I take Pabreca 125mg Capsule?

Generally, Pabreca 125mg Capsule is taken once daily for 21 consecutive days followed by 7 days off treatment to add up a complete cycle of 28 days. Take this medicine with food and at the same time each day. Swallow the whole capsules. Do not open, chew, or crush them. Do not take the capsules that are broken or cracked. If you vomit after taking Pabreca 125mg Capsule, do not take another dose and continue your regular dosing schedule.

Q. Do I need to use birth control method while using Pabreca 125mg Capsule?

Women of childbearing potential who are receiving Pabreca 125mg Capsule and their partners should use adequate contraceptive methods (e.g. double-barrier contraception such as condom and diaphragm). These methods should be used during therapy and for at least 3 weeks after completing therapy for females. Men who are on Pabreca 125mg Capsule therapy should use birth control methods for at least 14 weeks after completing the therapy.

Q. Does Pabreca 125mg Capsule affect fertility?

Male fertility may be affected during treatment with Pabreca 125mg Capsule. Thus, men may consider sperm preservation prior to beginning therapy with Pabreca 125mg Capsule.

Q. What are the serious side effects of Pabreca 125mg Capsule?

The serious side effects of Pabreca 125mg Capsule include shortness of breath, dizziness, weakness, unusual bleeding or bruising or nosebleeds. It may also cause fever, chills or signs of infection and fast, irregular or pounding heartbeat. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment.

References

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