Orif 3 Forte Tablet

Orif 3 Forte Tablet is a combination medicine used in the treatment of tuberculosis. It prevents the growth of the microorganisms that cause the infection.

Orif 3 Forte Tablet is a prescription medicine and it is to be taken it as suggested by the doctor. It should be taken in an empty stomach and take it at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine. The medicine may take some to show its effects on the symptoms. However, it is advised to consult the doctor if you feel an aggravation of the condition or if your condition does not improve.

Some common side effects of this medicine are nausea, vomiting, fever, dark- colored urine, sweating, increased saliva, etc. To cope up with the side effects, you should drink plenty of water. If any of the side effects get aggravated, you must consult your doctor immediately. Generally, serious side effects are rare. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Patients with liver and kidney ailments must take this medicine with proper consultation and caution. Pregnant or breastfeeding women should also consult with the doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. During the treatment, you must take adequate rest and eat a healthy diet for a faster recovery. While on the medication, your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.

• Tuberculosis (TB)

Tuberculosis (TB)
Orif 3 Forte Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It kills as well as stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Montorip

• Nausea
• Vomiting
• Fever
• Rash
• Dark colored urine
• Sweating
• Increased sputum production
• Salivation
• Watery eyes
• Peripheral neuropathy (tingling and numbness of feet and hand)
• Increased liver enzymes
• Jaundice
• Increased uric acid level in blood
• Gout

Take this medicine in the dose and duration as advised by your doctor. Orif 3 Forte Tablet is to be taken empty stomach.
Avoid Orif 3 Forte Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

Orif 3 Forte Tablet is a combination of three medicines: Isoniazid, Pyrazinamide and Rifampicin which treat tuberculosis. Isoniazid prevents the TB bacteria from forming their own protective covering while Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by these bacteria to make essential proteins and to reproduce. Together, they kill the bacteria and eradicate the infection. Pyrazinamide, on the other hand works by slowing the growth of these bacteria.

• Orif 3 Forte Tablet should be taken on an empty stomach but at the same time every day.
• Do not skip any doses and finish the full course of treatment even if you feel better.
• It may cause dizziness. Don't drive or do anything that requires mental focus until you know how Orif 3 Forte Tablet affects you.
• Avoid drinking alcohol while taking this medicine as this may increase the risk of side effects on the liver.
• Avoid taking hormone-based birth control methods as Orif 3 Forte Tablet may decrease their effectiveness.
• Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.

Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011. [Accessed 09 Apr. 2019] (online) Available from:

Drugs.com. Pyrazinamide. [Accessed 09 Apr. 2019] (online) Available from:

Drugs.com. Rifampicin. [Accessed 09 Apr. 2019] (online) Available from: