Niczole 20mg Capsule

Niczole 20mg Capsule is used to reduce the production of hydrochloric acid in the stomach. It treats gastroesophageal reflux disease (GERD), erosive esophagitis, gastritis and peptic ulcers. This capsule contains omeprazole, a proton pump inhibitor; it reduces symptoms associated with excess acid production, like indigestion, heartburn, acid reflux, hoarseness and stomach pain.

Niczole 20mg Capsule should be taken as prescribed by your doctor. The dose of the medication may be adjusted depending on the severity of your clinical symptoms. It is best to take this medicine an hour before your meal, preferably at the same time each day. You may continue taking this medicine even after you feel well.

Niczole 20mg Capsule may produce side effects such as vomiting, diarrhoea, dizziness, headache, flatulence (gas) and arthralgia (joint pain). These adverse effects usually go away on their own and should not be of any concern. Talk to your doctor if they persist or get worse.

Niczole 20mg Capsule is contraindicated (unsafe) for people with hypomagnesemia, anaemia, colitis, liver diseases or allergies to proton pump inhibitors like omeprazole. Always let your doctor know of any health conditions you might have. This drug is generally considered safe for most people.

Niczole 20mg Capsule reduces symptoms associated with too much acid in the stomach. It lowers the secretion of hydrochloric acid in the organ, which helps alleviate symptoms like heartburn, indigestion and stomach pain.

Niczole 20mg Capsule contains omeprazole which is used in the treatment of the following:

Niczole 20mg Capsule contains omeprazole, which works by blocking acid secretion in the stomach. This is done by inhibiting specific pumps in the stomach lining that secrete hydrochloric acid. The reduction in the acidity in the organ alleviates symptoms like indigestion, acid reflux, stomach pain and heartburn.

Omeprazole comes under the class of drugs called proton-pump inhibitors (PPI). It suppresses the final step in gastric acid production by binding to a specific enzyme system at the secretory surface of the gastric glands. This reduces both natural and stimulated acid production in the stomach for more than 24 hours. Lowering the acid levels enables omeprazole to treat gastroesophageal reflux disease and peptic ulcers. It controls acidity and prevents symptoms like heartburn and stomach pain.

1. Proton-pump inhibitor medications and osteoporosis

There are certain adverse effects of long-term administration of proton-pump inhibitors like omeprazole and pantoprazole on the bones. The main side effect that most studies point to is osteoporosis and the fractures related to it. Osteoporosis is a disease that develops over time, and it affects the bones, making them brittle and weak. And this can increase the risk of bone fractures. Clinical studies suggest that PPI users tend to have lower bone mineral density than non-PPI users. So it is advised to take vitamin D and calcium supplements that counter the effect of these medicines' long-term outcomes.

2. Proton-pump inhibitor rebound gastritis

If you stop taking PPIs, you may experience worsening symptoms, which are associated with gastritis (inflammation of the stomach’s lining). These symptoms include stomach upset, belching, hiccups, abdominal bleeding, nausea and vomiting. You might experience rebound symptoms for up to three weeks after you stop taking PPIs. You can avoid this by gradually stopping the use over a few weeks. During these few weeks, you may be advised to take antacids (calcium carbonate) or a histamine-2 antagonist (famotidine).

• Omeprazole (ncbi.nlm.nih.gov)
• Proton Pump Inhibitors (PPI) (ncbi.nlm.nih.gov)
• Omeprazole (medlineplus.gov)