Nesprex 20mg Tablet DT
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Introduction To Nesprex 20mg Tablet DT
Nesprex 20mg Tablet DT is a pain-relieving medicine. It is used in the treatment of moderate to severe pain. It helps to relieve pain and swelling of various conditions related to joints and muscles. It is usually given in cases where oral administration is unsuitable.
Nesprex 20mg Tablet DT is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep receiving the medicine until the doctor says it is okay to stop using the medicine.
The most common side effects of this medicine include injection site reactions (such as pain, redness, and swelling), vomiting, stomach pain, indigestion, diarrhea, headache, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
This medicine is not recommended for pregnant or breastfeeding women. Pregnant and breastfeeding mothers must consult with their doctors before using the medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
Uses of Nesprex 20mg Tablet DT
- Pain relief
Benefits of Nesprex 20mg Tablet DT
Pain relief
Nesprex 20mg Tablet DT is used for short-term relief of pain, inflammation, and swelling
in conditions that affect joints and muscles. It works by blocking chemical
messengers in the brain that tell us we have pain. It can help relieve pain in
conditions like rheumatoid arthritis and osteoarthritis or even after a dental
(tooth-related) surgery.
Take it as it is prescribed to get the most benefit. Do not take more or for
longer than needed as that can be dangerous. In general, you should take the
lowest dose that works, for the shortest possible time. This will help you to
go about your daily activities more easily and have a better, more active,
quality of life.
Side effects of Nesprex 20mg Tablet DT
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dracam
- Injection site reactions (pain, swelling, redness)
- Vomiting
- Stomach pain
- Nausea
- Headache
- Dizziness
How to use Nesprex 20mg Tablet DT
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Nesprex 20mg Tablet DT works
Nesprex 20mg Tablet DT is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).
Quick tips
- Nesprex 20mg Tablet DT helps relieve pain and swelling of various joints and muscles.
- It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
- Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Safety Advice
PregnancyCONSULT YOUR DOCTOR
Can I take Nesprex 20mg Tablet DT if I’m pregnant?
Nesprex 20mg Tablet DT is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
BreastfeedingSAFE IF PRESCRIBED
Can I take Nesprex 20mg Tablet DT if I’m breastfeeding?
Nesprex 20mg Tablet DT is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
AlcoholCAUTION
Is drinking alcohol while taking Nesprex 20mg Tablet DT safe?
Caution is advised when consuming alcohol with Nesprex 20mg Tablet DT. Please consult your doctor.
DrivingUNSAFE
Can I drive after taking Nesprex 20mg Tablet DT?
Nesprex 20mg Tablet DT may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
KidneyCAUTION
Can I take Nesprex 20mg Tablet DT if I have/had kidney diseases?
Nesprex 20mg Tablet DT should be used with caution in patients with severe kidney disease. Dose adjustment of Nesprex 20mg Tablet DT may be needed. Please consult your doctor. No dose adjustment is recommended in patients with mild to moderate kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine.
LiverCAUTION
Can I take Nesprex 20mg Tablet DT if I have/had liver diseases?
Nesprex 20mg Tablet DT should be used with caution in patients with liver disease. Dose adjustment of Nesprex 20mg Tablet DT may be needed. Please consult your doctor.
Frequently Asked Questions
Q. What is the difference between Nesprex 20mg Tablet DT and diclofenac?
Both Nesprex 20mg Tablet DT and diclofenac are pain killers. However, piroxicam is a non- selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Nesprex 20mg Tablet DT.
Q. What is the difference between Nesprex 20mg Tablet DT and naproxen?
Both Nesprex 20mg Tablet DT and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Nesprex 20mg Tablet DT.
Q. What is the difference between Nesprex 20mg Tablet DT and meloxicam?
Both Nesprex 20mg Tablet DT and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Nesprex 20mg Tablet DT.
Q. What is the difference between Nesprex 20mg Tablet DT and ketoprofen?
Both Nesprex 20mg Tablet DT and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Nesprex 20mg Tablet DT. Ketoprofen gel also showed excellent tolerability.
Q. What is the difference between Nesprex 20mg Tablet DT and tramadol?
Nesprex 20mg Tablet DT is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
Q. What is the difference between Nesprex 20mg Tablet DT and nimesulide?
Both Nesprex 20mg Tablet DT and nimesulide are pain killers. However, Nesprex 20mg Tablet DT is a non- selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Q. Can Nesprex 20mg Tablet DT be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Nesprex 20mg Tablet DT or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Nesprex 20mg Tablet DT.
Q. Are Nesprex 20mg Tablet DT and aspirin same?
No. Nesprex 20mg Tablet DT and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti- inflammatory and analgesic.
Q. Can Nesprex 20mg Tablet DT be used along with dexamethasone?
No. Nesprex 20mg Tablet DT should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Q. Can Nesprex 20mg Tablet DT be used with methocarbamol?
Yes. Methocarbamol can be used with Nesprex 20mg Tablet DT as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Can Nesprex 20mg Tablet DT be used along with paracetamol?
Yes. Paracetamol can be used with Nesprex 20mg Tablet DT as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Is Nesprex 20mg Tablet DT a NSAID?
Yes. Nesprex 20mg Tablet DT is a non-steroidal anti-inflammatory drug (NSAID).
Q. Is Nesprex 20mg Tablet DT a sulfa drug?
Nesprex 20mg Tablet DT is a sulphur containing compound. Nesprex 20mg Tablet DT can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Q. Is Nesprex 20mg Tablet DT a blood thinner?
No. Nesprex 20mg Tablet DT is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
Q. Is Nesprex 20mg Tablet DT a muscle relaxant?
No. Nesprex 20mg Tablet DT is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Q. Is Nesprex 20mg Tablet DT a narcotic?
No. Nesprex 20mg Tablet DT is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
Q. Can Nesprex 20mg Tablet DT be used in hypertension?
No. Nesprex 20mg Tablet DT is not a medication to control hypertension. It is important to note that Nesprex 20mg Tablet DT decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Nesprex 20mg Tablet DT.
Q. Can Nesprex 20mg Tablet DT be used along with Losartan?
No. Nesprex 20mg Tablet DT should not be combined with Losartan. It is important to note that Nesprex 20mg Tablet DT decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Nesprex 20mg Tablet DT.
Q. Can Nesprex 20mg Tablet DT be used with Lisinopril?
No. Nesprex 20mg Tablet DT should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Nesprex 20mg Tablet DT.
Q. Can Nesprex 20mg Tablet DT be used with calcium channel blocker?
Yes. Nesprex 20mg Tablet DT can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Q. Can Nesprex 20mg Tablet DT be used with Tizanidine?
Yes, Nesprex 20mg Tablet DT can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Q. Why is beta cyclodextrin added to Nesprex 20mg Tablet DT?
Yes. Nesprex 20mg Tablet DT can be combined with beta-cyclodextrin. Research has shown that combining Nesprex 20mg Tablet DT with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
Q. Are there any alternatives of Nesprex 20mg Tablet DT?
Yes. There are alternatives to Nesprex 20mg Tablet DT. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
Q. What are the contraindications for Nesprex 20mg Tablet DT?
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
Q. Can Nesprex 20mg Tablet DT be used in the treatment of allergy?
No. Nesprex 20mg Tablet DT is not a drug to treat allergy. It is a pain killer.
Q. How long does Nesprex 20mg Tablet DT work?
Nesprex 20mg Tablet DT is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Q. Can you get high by using Nesprex 20mg Tablet DT?
No. Nesprex 20mg Tablet DT is not known to cause high. It is a non-narcotic painkiller.
Q. Can Nesprex 20mg Tablet DT be used to treat menstrual cramp?
Nesprex 20mg Tablet DT is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
Q. Can I use Nesprex 20mg Tablet DT for a migraine?
Nesprex 20mg Tablet DT is not approved for the treatment of migraine. Research studies have shown that Nesprex 20mg Tablet DT is effective in significantly decreasing the pain associated with migraine without aura.
Q. Is Nesprex 20mg Tablet DT effective in back pain management?
Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Nesprex 20mg Tablet DT as the cause of back pain can be different for different person.
Q. Is Nesprex 20mg Tablet DT affective in gout management?
Yes. Nesprex 20mg Tablet DT can be given for the treatment of acute gout. Research studies have shown Nesprex 20mg Tablet DT to be highly effective in the treatment of acute gout.
Q. Can you donate blood when on the medication with Nesprex 20mg Tablet DT?
Yes. You can donate blood when on Nesprex 20mg Tablet DT. Do inform your doctor before donating blood.
Q. Can I use Nesprex 20mg Tablet DT if I am a diabetic?
Nesprex 20mg Tablet DT in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Nesprex 20mg Tablet DT so taking piroxicam can lead to increased risk of renal failure by many folds.
Q. Can I use Nesprex 20mg Tablet DT if I have a deranged renal function?
No. Nesprex 20mg Tablet DT should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Q. Can Nesprex 20mg Tablet DT lead to skin reactions?
Yes. Nesprex 20mg Tablet DT is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
Q. Can I use Nesprex 20mg Tablet DT if I am pregnant?
No. Nesprex 20mg Tablet DT should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Q. Can I use Nesprex 20mg Tablet DT if I have peptic ulcer disease?
No. Nesprex 20mg Tablet DT is contraindicated in cases of active peptic ulcer disease. Nesprex 20mg Tablet DT is known to cause gastric ulceration and bleeding.
Q. Can I use Nesprex 20mg Tablet DT if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti- inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Q. Can Nesprex 20mg Tablet DT lead to difficulty in conception?
Yes. Nesprex 20mg Tablet DT can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Q. Can Nesprex 20mg Tablet DT be used with diuretics?
No. Nesprex 20mg Tablet DT should not be used with diuretics. Nesprex 20mg Tablet DT reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Q. Can Nesprex 20mg Tablet DT be used with lithium?
No. Nesprex 20mg Tablet DT should not be used with lithium. Nesprex 20mg Tablet DT leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Q. Can Nesprex 20mg Tablet DT be used with warfarin?
No. Nesprex 20mg Tablet DT should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
Q. What increases the chances of getting a gastric ulcer when I am already taking Nesprex 20mg Tablet DT?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Q. Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Nesprex 20mg Tablet DT?
Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
Q. What are the serious side effects of Nesprex 20mg Tablet DT?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
References
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Written By:
Dr Advikka Ridhy
MBBS
RMO, Aster MIMS
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