Mycotube Plus Tablet

Mycotube Plus Tablet is a combination medicine used in the treatment of tuberculosis. It prevents the growth of the microorganisms that cause the infection.

Mycotube Plus Tablet is a prescription medicine and it is to be taken it as suggested by the doctor. It should be taken in an empty stomach and take it at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine. The medicine may take some to show its effects on the symptoms. However, it is advised to consult the doctor if you feel an aggravation of the condition or if your condition does not improve.

Some common side effects of this medicine are nausea, vomiting, fever, dark- colored urine, sweating, increased saliva, etc. To cope up with the side effects, you should drink plenty of water. If any of the side effects get aggravated, you must consult your doctor immediately. Generally, serious side effects are rare. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Patients with liver and kidney ailments must take this medicine with proper consultation and caution. Pregnant or breastfeeding women should also consult with the doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. During the treatment, you must take adequate rest and eat a healthy diet for a faster recovery. While on the medication, your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.

• Treatment of Tuberculosis (TB)

Treatment of Tuberculosis (TB)
Mycotube Plus Tablet is a combination of medicines that is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It kills as well as stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of RF 4

• Nausea
• Vomiting
• Rash
• Fever
• Dark colored urine
• Sweating
• Increased sputum production
• Salivation
• Watery eyes
• Peripheral neuropathy (tingling and numbness of feet and hand)
• Increased liver enzymes
• Jaundice
• Increased uric acid level in blood
• Visual impairment

Take this medicine in the dose and duration as advised by your doctor. Check the label before use. Mycotube Plus Tablet is to be taken empty stomach.
Avoid Mycotube Plus Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

Mycotube Plus Tablet is a combination of four medicines: Isoniazid, rifampicin, ethambutol and pyrazinamide which treat tuberculosis. Isoniazid works by preventing the TB bacteria from forming their own protective covering, while rifampicin inactivates a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce. Together, they kill the bacteria and eradicate the infection. Ethambutol and pyrazinamide on the other hand, work by slowing the growth of these bacteria.

• You have been prescribed Mycotube Plus Tablet for the treatment of tuberculosis.
• Take it on an empty stomach and preferably at the same time everyday.
• Try not to forget a dose, as this increases the risk of the bacteria becoming resistant to the medicine, and also increases the risk of getting side effects.
• It may discolour your urine, sweat, saliva and tears a reddish/orange colour. This is normal and not harmful.
• Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
• Avoid drinking alcohol while taking Mycotube Plus Tablet as this may increase the risk of side effects on the liver.
• It may cause vitamin B6 deficiency. Your doctor may prescribe vitamin B6 supplements to help avoid potential problems associated with its deficiency, such as inflammation of the nerves (neuritis).
• Use a reliable contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking Mycotube Plus Tablet as it may make hormonal contraceptives such as the pill less effective.
• Do not take indigestion remedies (antacids) within at least two hours of taking Mycotube Plus Tablet.
• Finish the full course of the medication, even if you feel better. Stopping the course early increases the risk of coming back of the infection.

Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011. [Accessed 09 Apr. 2019] (online) Available from:

Drugs.com. Rifampicin. [Accessed 09 Apr. 2019] (online) Available from:

Ethambutol. Ontario, Canada: Patheon Inc.; 2007. [Accessed 09 Apr. 2019] (online) Available from:

Drugs.com. Pyrazinamide. [Accessed 09 Apr. 2019] (online) Available from: