Mupirone Ointment

Mupirone Ointment is a topical antibiotic used to treat bacterial infections that affect the skin. This ointment contains mupirocin, a medicine that kills bacteria and prevents their growth. It is usually prescribed for bacterial skin infections such as impetigo and MRSA colonisation. Mupirocin is not used to treat skin infections caused by fungi or viruses.

Mupirone Ointment is meant for external use only. Clean and dry the affected area before application. Check the labels and instructions before applying. Unless advised by a doctor, do not apply this medicine on cuts, wounds, or burnt skin. Avoid contact with eyes or mouth. Follow your doctor’s instructions on the duration and dosage of this topical application.

Mupirone Ointment does not produce a lot of side effects when applied as prescribed. After using this ointment, you may experience a burning or stinging sensation, pain, rash or itching around the applied area. These signs will resolve once the skin gets used to the medicine. Contact your doctor if you experience rare but serious side effects like severe skin rash or itching, diarrhoea, stomach pain, and blistering.

This medicine is considered safe for most people. However, it is contraindicated (unsafe) if you have a fungal infection or a hypersensitivity to mupirocin and other ingredients of this ointment. Prolonged use of this medicine can lead to side effects due to the drug being slowly absorbed by the skin into your bloodstream. Long-term use can also result in the overgrowth of fungus on the skin.

Mupirone Ointment is a topical application used to primarily treat impetigo, a highly contagious bacterial skin infection characterised by red sores on the hands, feet, and face, especially around the nose and mouth. This infection usually lasts 10-12 days and affects children and infants.

Mupirone Ointment is also used for MRSA colonisation, a condition in which a bacteria named methicillin-resistant staphylococcus aureus infects the skin but doesn’t make the person sick. This medicine is sometimes used by doctors as first-line treatment for wounds and burns to prevent bacterial growth and infection in the affected area.

Mupirone Ointment contains mupirocin, an antibiotic, which treats this skin condition by killing and suppressing the growth of specific bacteria, such as Staphylococcus aureus and group A Streptococcus which are the causative agents on this skin infection. Mupirocin is highly effective against gram-positive bacteria, antibiotic-resistant and methicillin-resistant strains. It is also used against gram-negative bacteria like E. coli.

Your doctor will prescribe you Mupirone Ointment for a specific duration after assessing the extent of bacterial infection in the skin. Be sure to apply the ointment evenly on a clean and dry surface of the skin for the best results.

Mupirone Ointment works by killing or suppressing the growth of bacteria such as staphylococcus aureus and group A streptococcus that causes skin infections like impetigo.

Mupirone Ointment contains mupirocin, a highly effective antibiotic that works against gram-positive bacteria, antibiotic-resistant and methicillin-resistant strains. It is also used against gram-negative bacteria like E. coli.

Mupirocin works by reversibly inhibiting a DNA-like molecule within the bacteria called isoleucyl-transfer RNA. This is achieved by the antibiotic binding to an enzyme called the isoleucyl-transfer RNA (tRNA) synthetase, which the bacteria makes. This binding stops the enzyme from working to make bacterial protein and RNA - two things bacteria need to survive and grow.

• Mupirocin (medlineplus.gov)
• Habif's Clinical Dermatology: A Color Guide to Diagnosis and Therapy
• Color Atlas and Synopsis of Clinical Dermatology