Luprodex Depot 3.75mg Injection
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Introduction To Luprodex Depot 3.75mg Injection
Luprodex Depot 3.75mg Injection is used in the treatment of prostate cancer. It is also used to treat endometriosis (endometrium of the uterus grows excessively and causes symptoms like pain, heavy or irregular periods), uterine fibroids and central precocious puberty (very early puberty).
Luprodex Depot 3.75mg Injection is given as an injection under the skin by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Decreased libido, increased sweating, fatigue, muscle weakness, and hot flashes are some very common side effects of this medicine. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. It might cause menstrual periods to stop for a period of 7- 12 weeks, inform your doctor if menstrual bleeding continues even during the treatment.
Before taking this medicine, inform your doctor if you have a history of drinking alcohol, smoking, and osteoporosis. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Luprodex Depot 3.75mg Injection
- Treatment of Prostate cancer
- Treatment of Endometriosis
- Treatment of Uterine fibroids
- Treatment of Precocious puberty (premature puberty)
Benefits of Luprodex Depot 3.75mg Injection
Treatment of Prostate cancer
Prostate gland is a small walnut-sized gland that produces a fluid called
seminal fluid that nourishes and transports sperms in males. The most common
symptom of prostate cancer is difficulty with urination, but sometimes there
are no symptoms at all. Luprodex Depot 3.75mg Injection decreases or stops the growth of cancer
cells by decreasing the amount of testosterone (natural hormone in males) in
men. This also relieves difficulty in passing urine and makes it easier for
you to urinate.
Treatment of Endometriosis
Endometriosis is a condition where tissue like the lining of the womb starts
to grow in other places. The main symptoms include pain in your lower stomach
or back, period pain, pain during and after sex, constipation, diarrhea and
feeling sick. It can also make it difficult to get pregnant. Luprodex Depot 3.75mg Injection works
by preventing the lining of your womb and any endometriosis tissue from
growing too quickly. This will help relieve the symptoms you may have. This
medicine needs to be taken regularly to be effective and you may need other
medicines or procedures to help control endometriosis.
Treatment of Uterine fibroids
Uterine fibroids are non-cancerous growths of the uterus that often appear
during childbearing years. Luprodex Depot 3.75mg Injection helps control the symptoms associated
with uterine fibroids such as excessive menstrual bleeding, lower back pain,
and also reduces the size of the existing fibroids. It blocks the action of
the enzyme responsible for the growth of the broids. As a result, they
decrease in size and also stop growing further.
Treatment of Precocious puberty (premature puberty)
When puberty (change of a child’s body to adult structure and size) begins
before age 8 in girls and before age 9 in boys, it is considered precocious
puberty. Luprodex Depot 3.75mg Injection helps delay this early onset of adulthood and limits the
onset of precocious puberty. However, this medicine is given by a doctor and
should not be self-administered. Follow your doctor’s instructions carefully
for the most benefit.
Side effects of Luprodex Depot 3.75mg Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Luprodex
- Decreased libido
- Testicular atrophy
- Increased sweating
- Fatigue
- Muscle weakness
- Erectile dysfunction
- Bone pain
- Injection site reaction
- Hot flashes
How to use Luprodex Depot 3.75mg Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Luprodex Depot 3.75mg Injection works
Luprodex Depot 3.75mg Injection reduces the amount of sex hormones (testosterone in men and estrogen in women). It works by decreasing the blood levels of testosterone in males. Luprodex Depot 3.75mg Injection also acts by shutting off hormones made by the ovaries (female reproductive organs), so the estrogen (one of the hormones that causes females to have periods) level is lowered.
Quick tips
- Luprodex Depot 3.75mg Injection helps in the treatment of locally advanced or metastatic prostate cancer.
- It may also be used to treat endometriosis and uterine fibroids.
- It is given as an injection either under the skin or into a muscle.
- It may cause dizziness and visual disturbances. Don't drive or do anything that requires mental focus until you know how it affects you.
- It will cause menstrual periods to stop. Periods will resume 7-12 weeks after the final injection. Consult your doctor if you experience menstrual bleed despite treatment.
- Use non-hormonal methods of contraception such as condoms to prevent pregnancy during treatment, as this medicine may be harmful to a developing baby.
- Long term treatment may lead to bone loss and a higher risk of bone fractures, especially if you are a heavy drinker, a smoker, or have a family history of osteoporosis.
Safety Advice
PregnancyUNSAFE
Can I take Luprodex Depot 3.75mg Injection if I’m pregnant?
Luprodex Depot 3.75mg Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
BreastfeedingCONSULT YOUR DOCTOR
Can I take Luprodex Depot 3.75mg Injection if I’m breastfeeding?
Information regarding the use of Luprodex Depot 3.75mg Injection during breastfeeding is not available. Please consult your doctor.
AlcoholCAUTION
Is drinking alcohol while taking Luprodex Depot 3.75mg Injection safe?
Caution is advised when consuming alcohol with Luprodex Depot 3.75mg Injection. Please consult your doctor.
DrivingUNSAFE
Can I drive after taking Luprodex Depot 3.75mg Injection?
Luprodex Depot 3.75mg Injection may cause side effects which could affect your ability to drive. Do not drive or operate machinery if you experience drowsiness, dizziness or visual disturbances whilst being treated with Luprodex Depot 3.75mg Injection.
KidneyCONSULT YOUR DOCTOR
Can I take Luprodex Depot 3.75mg Injection if I have/had kidney diseases?
There is limited information available on the use of Luprodex Depot 3.75mg Injection in patients with kidney disease. Please consult your doctor.
LiverCONSULT YOUR DOCTOR
Can I take Luprodex Depot 3.75mg Injection if I have/had liver diseases?
There is limited information available on the use of Luprodex Depot 3.75mg Injection in patients with liver disease. Please consult your doctor.
Frequently Asked Questions
Q. Is Luprodex Depot 3.75mg Injection a chemotherapy medicine?
No, Luprodex Depot 3.75mg Injection is not a chemotherapy medicine. Luprodex Depot 3.75mg Injection is a synthetic hormone analogue medicine which is used for the treatment of hormone-dependent conditions in men and women.
Q. Does Luprodex Depot 3.75mg Injection stop periods?
Yes, the periods tend to stop while taking Luprodex Depot 3.75mg Injection injections as this medicine alters the reproductive hormones in females. Sometimes, there can be vaginal bleeding in few cases. If this occurs, please contact your doctor to get yourself assessed and follow the direction of your doctor.
Q. Is Luprodex Depot 3.75mg Injection a hormonal medicine and can it be given in pregnancy?
Yes, Luprodex Depot 3.75mg Injection is a hormonal medicine which alters the reproductive hormones when given in females. This medication is not recommended for use in women who are or may become pregnant because this can harm the fetus in the womb. Using this medicine during pregnancy may also lead to abortion of the baby. Do inform your doctor if you are pregnant or are planning to get pregnant before starting this medication.
Q. Can taking Luprodex Depot 3.75mg Injection affect my bones?
Yes, there are chances of Luprodex Depot 3.75mg Injection affecting your bones. Using Luprodex Depot 3.75mg Injection may cause a decrease in bone mineral density and make the bones weaker. In women, bone density should be assessed before starting the treatment. Special care and monitoring should be done in women with increased risk of osteoporosis. If at all needed, additional medicines may be given to prevent the development of osteoporosis in patients with decreased bone mineral density.
Q. Can Luprodex Depot 3.75mg Injection cause diabetes or increased blood sugar?
Yes, Luprodex Depot 3.75mg Injection may cause an increase in blood sugar levels, worsening the blood glucose control in patients with diabetes. It can even increase the risk of developing diabetes. Therefore, you must monitor the blood glucose and/or glycosylated hemoglobin (HbA1c) from time to time to keep a track of the glucose control and inform your doctor in case you develop any problem. Diabetic patients when prescribed this medication should monitor the sugar levels more frequently while taking this treatment.
References
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Written By:
Dr Advikka Ridhy
MBBS
RMO, Aster MIMS
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