L-Aspase 10000IU Injection
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Introduction To L-Aspase 10000IU Injection
L-Aspase 10000IU Injection is used in the treatment of some kinds of cancer of white blood cells (leukemia). It may also be used to treat other types of cancer as determined by your doctor. It may be used on its own, or sometimes given together with certain other medicines as part of combination chemotherapy.
L-Aspase 10000IU Injection is given as an injection by the doctor, but try to have it the same time each day to make sure it has the best effect. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effect of this medicine includes breathlessness, rash, vomiting, angioedema (swelling of deeper layers of skin), and nausea. It might cause increased blood sugar levels, hence regular blood tests are required to monitor your blood sugar levels, response to the therapy, and any side effects. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well.
This medicine may lower your body's resistance and increase susceptibility to infections. Infections can sometimes be life-threatening. It is important to use effective contraception to avoid getting pregnant or fathering a child during treatment. Before taking this medicine, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Uses of L-Aspase 10000IU Injection
- Blood cancer (Acute lymphocytic leukemia)
Benefits of L-Aspase 10000IU Injection
Blood cancer (Acute lymphocytic leukemia)
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues,
that decreases the body's ability to fight infection. L-Aspase 10000IU Injection kills or
stops the growth of cancer cells and also prevents the multiplication of
cancer cells. It is a potent and very toxic medicine and you should discuss
the risks and benefits with your doctor. You should avoid drinking alcohol
while having this treatment and drink plenty of water to stay hydrated.
Side effects of L-Aspase 10000IU Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Asparget
- Breathlessness
- Rash
- Vomiting
- Angioedema (swelling of deeper layers of skin)
- Edema (swelling)
- Nausea
- Fatigue
- Increased liver enzymes
- Diarrhea
- Decreased blood pressure
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Low albumin level in blood
- Increased glucose level in blood
- Hives
How to use L-Aspase 10000IU Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How L-Aspase 10000IU Injection works
Asparaginase belongs to class of medications called antineoplastic agents. Asparaginase is an enzyme that interferes with natural processes necessary for cancer cell growth, thereby killing or stopping the growth of cancer cells.
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Quick tips
- L-Aspase 10000IU Injection is given as an injection into the veins, muscles or under the skin by the healthcare provider.
- It is advisable to drink plenty of fluids and stay hydrated while taking this medication.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
- You may need to have blood tests to monitor your blood cells, liver function and kidney function during treatment.
- It can cause an increase in blood sugar levels. Hence, monitor your blood sugar level regularly.
Safety Advice
PregnancyCONSULT YOUR DOCTOR
Can I take L-Aspase 10000IU Injection if I’m pregnant?
L-Aspase 10000IU Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
BreastfeedingCONSULT YOUR DOCTOR
Can I take L-Aspase 10000IU Injection if I’m breastfeeding?
L-Aspase 10000IU Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
AlcoholCONSULT YOUR DOCTOR
Is drinking alcohol while taking L-Aspase 10000IU Injection safe?
It is not known whether it is safe to consume alcohol with L-Aspase 10000IU Injection. Please consult your doctor.
DrivingSAFE
Can I drive after taking L-Aspase 10000IU Injection?
L-Aspase 10000IU Injection does not usually affect your ability to drive.
KidneySAFE IF PRESCRIBED
Can I take L-Aspase 10000IU Injection if I have/had kidney diseases?
L-Aspase 10000IU Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of L-Aspase 10000IU Injection may not be needed in these patients. Please consult your doctor.
LiverCONSULT YOUR DOCTOR
Can I take L-Aspase 10000IU Injection if I have/had liver diseases?
There is limited information available on the use of L-Aspase 10000IU Injection in patients with liver disease. Please consult your doctor. However, regular monitoring of liver function tests is advised while you are taking this medicine.
Frequently Asked Questions
Q. When should I call my doctor right away?
Get medical help right away if you have signs of allergic reaction such as difficulty breathing, rash, hives, itching, and blisters. Also, let your doctor know if you experience severe headache, chest pain, severe abdominal pain, and swelling in various parts of the body.
Q. Can L-Aspase 10000IU Injection damage my liver?
L-Aspase 10000IU Injection may affect the liver and cause serious or even life-threatening damage to the liver. Inform your doctor immediately if you notice severe stomach pain (upper right side), dark urine, clay-colored stools, tiredness, itching, or jaundice (yellowing of the skin or eyes).
Q. I am experiencing nausea and extreme tiredness. Is this due to L-Aspase 10000IU Injection?
Nausea and fatigue or tiredness are some of the common side-effects of this medicine. Eat smaller, more frequent meals to reduce the feeling of nausea. Avoid food that is salty, spicy, fried, or fatty. Take plenty of rest and do light exercise daily to keep yourself active and reduce fatigue.
Q. How to get relief from diarrhea while on treatment with L-Aspase 10000IU Injection?
Food items with soluble fiber can help relieve diarrhea as they help absorb excess fluid from the body. These food items include bananas (ripe), orange, boiled potatoes, white rice, curd, and oatmeal. Diarrhea can cause dehydration in the body, so drink 8-10 glasses of water to avoid dehydration. You can also have soups and juice frequently to hydrate yourself.
Q. I have noticed some changes in my skin after taking L-Aspase 10000IU Injection. What should I do?
Use a moisturizer to get relief from rashes, dry, and itchy skin during the treatment. Avoid sun exposure. Wear SPF 30 (or higher) sunblock and protective clothing. However, if you develop yellow discoloration of your skin, inform your doctor immediately as this could be a sign of a liver problem.
Q. Can the use of L-Aspase 10000IU Injection cause hyperglycemia?
Yes, L-Aspase 10000IU Injection can cause hyperglycemia or increase blood sugar level. Monitor your sugar level regularly and immediately inform your doctor if you see a spike in your level.
Q. I am noticing swelling and frequent muscle cramps. Should I inform my doctor?
You might experience weakness, muscle cramps and swelling in different parts of your body. This is due to low levels of albumin, an important protein in your body. Consult your doctor who will recommend blood tests to monitor your albumin levels.
Q. Should I avoid any food and drinks while taking L-Aspase 10000IU Injection?
You can continue with your normal diet unless your doctor tells you otherwise. However, it is advisable to sip water regularly to prevent you from becoming dehydrated, eating small, simple but nourishing snacks every few hours rather than large meals, and sucking on hard candy or popsicles to prevent nausea and vomiting.
Q. What should I avoid during my treatment with L-Aspase 10000IU Injection?
During your treatment, it is advisable to avoid caffeine as it can make you feel dehydrated, avoid fatty fried, spicy, and overly sweet foods, as they may induce nausea, avoid alcohol and smoking. It is also advisable to avoid crowds or people with colds, as you may be at risk of infection as well as sun exposure to prevent rashes and dry skin. Do not have immunizations/vaccinations without the consent of your doctor. Use caution with sharp objects like razors or nail cutters and avoid activities such as contact sports to lower the chance of getting cut, bruised, or injured.
References
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Written By:
Dr Advikka Ridhy
MBBS
RMO, Aster MIMS
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