Invega Sustenna 100mg Injection

Invega Sustenna 100mg Injection is used in the treatment of schizophrenia (a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave) and mania.

Invega Sustenna 100mg Injection is given under the supervision of a healthcare professional. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. This medication should not be stopped suddenly without talking to your doctor as it may worsen your symptoms. However, discontinue this medicine immediately if you experience neuroleptic malignant syndrome (NMS), characterized by fever, muscle rigidity, and altered consciousness.

Some common side effects of this medicine include injection site reactions (pain, swelling, redness), nystagmus (involuntary eye movement), and tremor. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.

You should be cautious if you are using this medicine as it may increase the risk of developing diabetes, so it is better to monitor glucose regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts while taking this medicine.

There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.

• Schizophrenia
• Mania

Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Invega Sustenna 100mg Injection helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.

Mania
Mania means extremely excited or elevated mood. Invega Sustenna 100mg Injection helps calm the mood and relax the nerves. This stabilises the mood and prevents the symptoms of mania from recurring again. Taking Invega Sustenna 100mg Injection will ensure that you have a better social life and are able to do daily activities more comfortably.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Invega Sustenna

• Abnormal involuntary movements
• Dizziness
• Injection site reactions (pain, swelling, redness)
• Nystagmus (involuntary eye movement)
• Sleepiness
• Tremors

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Invega Sustenna 100mg Injection is an atypical antipsychotic. It works by affecting the levels of chemical messengers (dopamine and serotonin) to improve mood, thoughts and behavior.

• Invega Sustenna 100mg Injection is given as an injection into muscle by a doctor only.
• To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
• Use caution while driving or doing anything that requires concentration as Invega Sustenna 100mg Injection can cause dizziness and sleepiness.
• It may cause an increase in weight, blood sugar, cholesterol, and triglycerides (fat). Eat healthy, exercise, and monitor your levels regularly.
• Monitor your blood sugar regularly as Invega Sustenna 100mg Injection can affect blood sugar levels.
• Do not stop taking Invega Sustenna 100mg Injection without talking to your doctor first as it may cause a worsening of symptoms.

Stahl SM, editor. Paliperidone. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 503-508.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1047-48.

Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Paliperidone. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:

Drugs.com. Paliperidone. [Accessed 25 Mar. 2019] (online) Available from: