Graincide Tablet SR

Graincide Tablet SR is a combination of two medicines that helps in preventing migraine. This medicine is not used for treatment of acute migraine attack.

Graincide Tablet SR should be taken on empty stomach, but try to have it same time regularly at a fixed time preferably at night. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. Lifestyle modifications like avoiding stress, smoking, and processed food items may help this medicine work better.

Few common side effects of this medicine include weight gain, slow heart rate, tiredness, depression, drowsiness and cold extremities. It may cause sleepiness so try not to drive or do anything that requires mental focus or rise slowly while from sitting position. The drug has the ability to hide the symptoms of the blood sugar level, hence monitor your blood sugar level regularly as well as blood pressure while taking this medicine.

Before taking this medicine, let your doctor know if you have liver or kidney, or depression disease, or if you are pregnant or breastfeeding. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.

• Prevention of Migraine

Prevention of Migraine
Graincide Tablet SR helps improve the flow of blood in your brain and prevents abnormal activity of muscles that triggers migraines. It is a very effective medicine for preventing migraine attacks, however, it does not treat an attack that has already started. By preventing and reducing the frequency migraine attacks, the medicine can help you carry out your daily activities and improve your quality of life.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Prosal-S

• Weight gain
• Slow heart rate
• Tiredness
• Depression
• Drowsiness
• Abnormal dreams
• Cold extremities

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Graincide Tablet SR is to be taken empty stomach.

Graincide Tablet SR is a combination of two medicines: Propranolol and Flunarizine, which prevents migraine. Propranolol is a beta blocker and Flunarizine is a calcium channel blocker. They work by stabilizing the reactive nerve cells and increasing the threshold to migraine activation. They also inhibit cortical spreading depression (CSD- electric waves that move across the brain and cause pain and inflammation).

• You have been prescribed Graincide Tablet SR for prevention of migraine headaches.

• Do not take it to treat an acute attack of migraine.

• Some tips that may help avoid a migraine attack:

  • Have your meals at the same time everyday
  • Avoid bright lights and extreme temperatures
  • Avoid loud music and noisy places
  • Avoid chocolates, cheese, processed food, alcohol and smoking
  • Get sufficient sleep and avoid stress

• It should be taken at night-time before going to bed.

• It may cause sleepiness. Don't drive or do anything that requires mental focus until you know how Graincide Tablet SR affects you.

• keep taking it regularly every day, even if you don't have any symptoms.

Propranolol. Barnstaple, Devon: Actavis; 2018. [Accessed 11 Apr. 2019] (online) Available from:

Drugs.com. Flunarizine. [Accessed 25 Mar. 2019] (online) Available from:

Drugs.com. Propranolol Pregnancy and Breastfeeding Warnings. [Accessed 20 Mar. 2019] (online) Available from:

Flunarizine. High Wycombe, Buckinghamshire: Janssen Cilag Ltd.; 2009 [revised Feb. 2014]. [Accessed 11 Apr. 2019] (online) Available from: