Glofty-OZ Suspension

MRP
₹ 31
PRESCRIPTION REQUIRED
YES
MANUFACTURER/ MARKETER
Globus Remedies Ltd
QUANTITY
30 ml Suspension

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Introduction To Glofty-OZ Suspension

Glofty-OZ Suspension is used to treat bacterial and protozoan infections of the lungs, skin, reproductive system and gastrointestinal tract. This drug is a combination of two antibiotics: Ofloxacin and ornidazole. The first kills bacteria, while the latter kills parasitic organisms called protozoa. This medication can be prescribed for pneumonia, urethritis, dysentery, amebiasis, giardiasis and other microbial infections.

Glofty-OZ Suspension should be taken as advised by your doctor. It is best to take them whole after your meal with plenty of fluids to avoid stomach discomfort. All antibiotic therapies should be completed and not stopped midway, even if you feel well. Try not to miss a dose, and avoid taking twice the amount to compensate for a missed dose.

Side effects of Glofty-OZ Suspension include nausea, tiredness, dry mouth and headache. They typically last for a short period and should not be of any concern. Your doctor may also prescribe a PPI medicine (drugs that reduce stomach acid) along with the antibiotic to counter its gastric side effects.

Glofty-OZ Suspension is contraindicated for people with a history of liver diseases, renal failure, nerve disorders, and allergies to either ofloxacin or ornidazole. Always let your doctor know of any health conditions you might have. Generally, this combination drug is considered safe for most people.

Uses of Glofty-OZ Suspension

Glofty-OZ Suspension contains two antibiotics used in the treatment of bacterial infections and protozoan diseases. These infections affect various parts of the body, including the lungs, urinary tract, skin, reproductive system and gastrointestinal tract.

This medication is prescribed for the following:

How Glofty-OZ Suspension works

Glofty-OZ Suspension is a combination of two antimicrobial drugs: an antibiotic and an antiprotozoal. When administered together, both kill the harmful bacteria and protozoan parasites by blocking certain enzymes and producing toxic compounds that kill the infective agent.

Glofty-OZ Suspension includes two active ingredients: ofloxacin and ornidazole. Let’s look at what they do individually to understand how they work when combined.

Ofloxacin is an antibiotic that comes under the class of antibiotic drugs called fluoroquinolones. They work as broad-spectrum drugs (which means they are functional against a wide range of bacteria) and are used to kill both gram-positive and gram-negative bacteria.

The way ofloxacin works is by preventing the bacterial cells from multiplying. It blocks or inhibits certain enzymes within the bacterial cell, such as DNA gyrase, type II topoisomerase, and topoisomerase IV enzymes. These enzymes are necessary for the separation of bacterial DNA, which is crucial for cell division. When these enzymes are blocked, the DNA breaks, and the bacteria die.

Ornidazole is a nitroimidazole antimicrobial. It works against both parasites (protozoans) and anaerobic bacteria. The mechanism of action involves the activation of this drug by the enzymes the microbes produce; upon activation, certain toxic compounds are formed, which are harmful to the cells of these microbes. This results in the damage of proteins, membranes and the DNA found inside the cell.

Ornidazole is used to treat trichomoniasis (a sexually transmitted disease caused by Trichomonas vaginalis), giardiasis (a diarrheal disease caused by Giardia duodenalis), and amebiasis (an intestinal infection caused by Entamoeba histolytica) - all protozoal infections.

Dosage

Take Glofty-OZ Suspension as prescribed by your doctor for the exact duration. Do not discontinue the usage of this medicine even if you feel better. Take this medicine as a whole with ample water. Do not chew or crush. You may take it after food to reduce the chances of stomach upset. You may feel slightly sleepy/drowsy after taking this medication.

Take any missed medication as soon as you recall if you have missed a dose. If it is time for your next dose, ignore the missed dose and continue with the next one. To compensate for a missed dose, avoid taking twice the amount.

Taking way more than the prescribed dose can lead to an overdose. If you experience symptoms like shivering, swelling and numbness of the face, slurred speech and dizziness - rush to your nearest hospital.

Safety Advice

Glofty-OZ Suspension is not recommended for people with severe liver/kidney diseases, myasthenia gravis, diabetes, colitis, nerve-related problems and allergies to either ofloxacin or ornidazole. Always let your doctor know of any health conditions you might have.

Glofty-OZ Suspension may cause tendon rupture and tendonitis since it contains fluoroquinolone. Please consult your doctor immediately if you experience pain, swelling or inflammation in your tendons while taking medicine.

sdsPregnancyCaution

Can I take Glofty-OZ Suspension if I’m pregnant?

sdsBreastfeedingCaution

Can I take Glofty-OZ Suspension if I’m breastfeeding?

sdsAlcoholUnsafe

Is drinking alcohol while taking Glofty-OZ Suspension safe?

sdsDrivingUnsafe

Can I drive after taking Glofty-OZ Suspension?

Drug interactions

Drug-Food interaction

Consumption of alcohol while taking Glofty-OZ Suspension may worsen side effects. Avoid consuming dairy products within 2 hours of taking this medication. It is best to avoid caffeine products as well.

Drug-Disease interaction

Glofty-OZ Suspension may not be given to people with central nervous system disorders to avoid side effects like tremors, anxiety, restlessness and hallucinations. This medication is contraindicated for people with colitis (inflammatory disease of the colon), neurological disorders, diabetes, myasthenia gravis and severe kidney and liver diseases.

Drug-Drug interaction

Consult your doctor if you are currently taking the following medicines: nonsteroidal anti-inflammatory drugs (ibuprofen, diclofenac), caffeine, blood thinners (warfarin, acenocoumarol ), immunosuppressant (cyclosporine), methylxanthine derivatives (theophylline, aminophylline), antidiabetic drugs (insulin, glibenclamide, metformin), antacids (aluminium hydroxide, magnesium carbonate), antibiotics (sulfamethoxazole, trimethoprim, metronidazole, azithromycin, erythromycin), and medicines to treat chronic alcoholism (disulfiram).

Drug-Drug Interactions Checker List:

Caffeine Warfarin Acenocoumarol Cyclosporine Disulfiram Theophylline Aminophylline Insulin Glibenclamide Metformin Aluminium hydroxide Magnesium carbonate Sulfamethoxazole Trimethoprim Metronidazole Azithromycin erythromycin

Frequently Asked Questions

Q. What is Glofty-OZ Suspension’s content?

Glofty-OZ Suspension is a combination of two antibiotics: ofloxacin and ornidazole. The first kills bacteria, while the latter kills parasitic organisms called protozoa.

Q. Is Glofty-OZ Suspension for loose motion?

Yes, Glofty-OZ Suspension is used to treat stomach and intestinal infections that present with loose stools and bloody diarrhoea. This medication stops and prevents loose motions.

Q. What is Glofty-OZ Suspension used for?

Glofty-OZ Suspension is used to treat bacterial and protozoan infections of the lungs, skin, reproductive system and gastrointestinal tract.

Q. Can Glofty-OZ Suspension be used for constipation?

No, Glofty-OZ Suspension is an antimicrobial medicine used in the treatment of diarrhoea. It can not be used to treat constipation. It works by killing parasites and bacteria.

Q. What are the side effects of Glofty-OZ Suspension?

The common side effects of Glofty-OZ Suspension include nausea, tiredness, stomach pain and a mild headache. Contact your doctors if problems persist or get worse.

Q. Should I take Glofty-OZ Suspension before food or after?

Glofty-OZ Suspension can be taken with or without food. For the best results, take this medicine after food, and avoid dairy products and caffeinated drinks.

Q. Can I stop taking Glofty-OZ Suspension when my symptoms are relieved?

Glofty-OZ Suspension includes antibiotic medicines; thus, this therapy should not be stopped even when you feel better. Complete the course as per your doctor’s instruction.

References

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