Gabaprime Plus Gel

Gabaprime Plus Gel is a prescription medicine used for the treatment of neuropathic pain. It works by first cooling and then warming up the skin. Thus, it calms the damaged or overactive nerves by acting on the brain, thereby decreasing the sensation of pain.

Gabaprime Plus Gel is for external use only. You should use this in the dose and duration advised by your doctor. Clean and dry the affected area before applying this medicine to the skin. You should always wash your hands after applying it unless hands are the affected area.

There are no major side effects associated with this medicine, but it can cause some application site burning, irritation, itching or redness. However, these side effects are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you.

• Neuropathic pain

Neuropathic pain
Gabaprime Plus Gel is used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles or spinal cord injury. It interferes with pain signals that travel through the damaged nerves and the brain. Using this medicine regularly will improve your physical and social functioning and overall quality of life.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Gabaprime

• Application site reactions (burning, irritation, itching and redness)

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

Gabaprime Plus Gel is a combination of three medicines: Gabapentin, Lidocaine, and Baclofen. Gabapentin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Lidocaine is a local anesthetic which works by blocking pain signals from the nerves to brain thereby decreasing the sensation of pain. Baclofen is a muscle relaxant. It works on the centres in the brain and spinal cord to relieve muscle stiffness or spasm without reduction in strength. This improves pain and movement of muscles. Together, they relieve neuropathic pain (pain from damaged nerves).

• Gabaprime Plus Gel is used to treat certain types of long-lasting pain caused by damage to nerves.
• Avoid contact with the eyes, mouth, nose and rinse thoroughly in case of accidental contact or seek medical help in case of swallowing.
• Inform your doctor if you are taking any other pain-relieving medicines.
• Along with taking Gabaprime Plus Gel, your doctor might advise you to undergo physiotherapy to get relief from pain.

Stahl SM, editor. Gabapentin. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 275-77.

McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 599.

Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 410.

White PF, Katzung BG. Skeletal Muscle Relaxants. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 463.

White PF, Katzung BG. Skeletal Muscle Relaxants. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 451-468.