Epotrend 2000 Injection

Epotrend 2000 Injection is a medicine that helps your bone marrow to produce more red blood cells. It is used to treat a type of anemia caused by kidney disease. It is also used to treat anemia caused by cancer chemotherapy and by taking medicines to treat HIV.

Epotrend 2000 Injection is given by injection either under the skin or into a vein which will be decided by your doctor. Usually, the injections are given by a nurse or doctor. The dose depends on your body weight and the cause of your anemia. Iron supplements both before and during treatment may make this treatment more effective. Epotrend 2000 Injection needs to be stored in a fridge but used at room temperature.

The most common side effects of taking this medicine include nausea, vomiting, fever, and increased blood pressure. It may also cause flu-like symptoms such as headache, tiredness, dizziness and aches and pains. These side effects are most common at the start of treatment but if they persist your doctor may be able to suggest ways of preventing or reducing them. Tell your doctor straight away if you get any serious side effects, including seizures (fits). Sometimes this medicine can cause serious blood clots that need urgent medical attention.

Before using Epotrend 2000 Injection you should tell your doctor if you have uncontrolled high blood pressure, heart disease, or gout (disease of joint pain). You should also tell him/her what other medicines you are taking in case they affect this treatment. Your blood pressure should be checked often during this treatment by you or your doctor. You may also need other regular medical tests to be sure this medicine is not causing harmful effects. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.
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There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.**

• Treatment of Anemia due to chronic kidney disease
• Treatment of Anemia due to cancer chemotherapy

Treatment of Anemia due to chronic kidney disease
Epotrend 2000 Injection is a man-made protein that helps your bone marrow to produce more red blood cells. It is used to treat anemia which is caused by kidney disease in adults and children who are on dialysis. Anemia is a condition where your body does not have enough red blood cells to carry oxygen around your body. This medicine helps reduce weakness and tiredness that you may be experiencing due to anemia. The injection is usually given by a doctor after a dialysis treatment.

Treatment of Anemia due to cancer chemotherapy
Anemia is a condition where your body does not have enough red blood cells to carry oxygen around your body. Epotrend 2000 Injection is a man-made protein that works by stimulating the bone marrow (soft tissue inside the bones) to produce more red blood cells. The natural human form of this protein may be reduced when you are having chemotherapy to treat some types of cancer. An injection of the medicine can reduce the need to have a blood transfusion. You may also be given iron supplements to make the treatment more effective.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Espogen

• High blood pressure
• Nausea
• Vomiting
• Fever
• Rash
• Joint pain
• Headache
• Insomnia (difficulty in sleeping)
• Chills
• Cough
• Bone pain
• Muscle spasm
• Dizziness
• Vascular occlusion
• Injection site irritation
• Stomatitis (Inflammation of the mouth)
• Weight loss
• Decreased white blood cell count (lymphocytes)
• Increased glucose level in blood
• Blood clot in the blood vessels

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Epotrend 2000 Injection is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells.

• Epotrend 2000 Injection helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.

• It is given as a single injection under your skin.

• Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells and electrolytes such as potassium in your blood.

• Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, problems with your eyesight, nausea, vomiting or fits (seizures).

• Stop taking Epotrend 2000 Injection and inform your doctor if you develop shortness of breath or skin rash.

Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1071-72.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 479-81.

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