Epalpex 150 SR Tablet

Epalpex 150 SR Tablet is used to treat diabetic nerve pain. Poorly controlled diabetes can eventually lead to diabetic nerve disease (neuropathy) as a complication. This medicine helps to relieve symptoms like burning pain and numbness seen in people with diabetic nerve disease.

Epalpex 150 SR Tablet belongs to a group of medicines known as Aldose reductase inhibitors. It can be taken with or without food but you should try to take it at the same time every day. This will help you to remember to take it. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms. It may take up to 3 months to get the full benefits of this medicine, but you should keep taking it regularly. Do not stop taking it without asking your doctor, otherwise, your condition may worsen.

This medicine is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. You should also continue taking other medicines prescribed by your doctor for blood sugar control. Keeping your blood sugar levels under control will help this medication work better.

The most common side effects of this medicine include nausea, vomiting, and abnormalities in liver function tests (increased liver enzymes). Most side effects are temporary and improve as your body gets used to the medicine. Please consult your doctor if any of these bother you or do not go away.

Before taking this medicine, let your doctor know if you have any kidney or liver problems. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Avoid any alcohol intake while taking it as this may increase the risk of developing some side effects.

• Diabetic nerve pain

Diabetic nerve pain
High levels of blood sugar (glucose) levels in diabetic patients can cause damage to nerves and this can cause pain sensation. Epalpex 150 SR Tablet blocks the action of those chemicals that are responsible for causing pain sensation and even inflammation of the nerves due to diabetes. By relieving pain, it helps improve your quality of life. Keep taking it as advised by the doctor to get the most benefit.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Alrista

• Nausea
• Vomiting
• Abnormal liver function

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Epalpex 150 SR Tablet may be taken with or without food, but it is better to take it at a fixed time.

Epalpex 150 SR Tablet is an aldose reductase inhibitor. It blocks the accumulation of sorbitol in cells, which has been related to causing diabetic nerve disease.

• Adherence to antidiabetic therapy can delay the onset of or prevent diabetic nerve disease.

• If you have existing diabetic nerve disease, wear proper footwear and examine your feet every day to detect lesions early.

• If you have a foot injury or open wound, avoid engaging in weight-bearing activities.

Ramirez MA, Borja NL. Epalrestat: An aldose reductase inhibitor for the treatment of diabetic neuropathy. Pharmacotherapy. 2008;28(5):646-55. [Accessed 18 Mar. 2019] (online) Available from:

Hotta N, Akanuma Y, Kawamori R, et al. Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial. Diabetes Care. 2006;29(7):1538-44. [Accessed 27 Mar. 2017] (online) Available from: