Encef 1000mg Injection

MRP
₹ 73.4
PRESCRIPTION REQUIRED
YES
MANUFACTURER/ MARKETER
Kentreck Laboratories Pvt Ltd
QUANTITY
1 Injection
SALT COMPOSITION
Ceftriaxone (1000mg)

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Introduction To Encef 1000mg Injection

Encef 1000mg Injection contains ceftriaxone, which belongs to the group of antibiotics called cephalosporin. It is used to treat severe gram-negative infections, including pneumonia, meningitis, pyelonephritis, and gonorrhoea. This medication is also prescribed for bacterial infections in the ear, nose, abdomen, skin and urinary tract.

Encef 1000mg Injection is injected directly into a vein/muscle or given as a drip/cannula under the supervision of your doctor. This medicine is administered at evenly spaced intervals as per your doctor's prescription. Do not stop taking this antibiotic before the prescribed dosage is finished, even if you feel better. Stopping the medicine too early can lead to a return of or worsening of the symptoms.

Side effects of Encef 1000mg Injection include nausea, vomiting, vaginal itching, rash and diarrhoea. You might also notice a slight redness and warmth in the area of injection. These adverse effects usually go away on their own and should not be of any concern. Talk to your doctor if they persist.

Encef 1000mg Injection is contraindicated (unsafe) for people with anaemia, congestive heart failure, colitis, liver diseases or allergies to cephalosporins like ceftriaxone. Always let your doctor know of any health conditions you might have. Generally, this medicine is considered safe for most people.

Uses of Encef 1000mg Injection

Encef 1000mg Injection contains a third-generation cephalosporin called ceftriaxone. It is a highly effective antibiotic that treats bacterial infections in various organs, including the brain (unlike many other antibiotics), like meningitis. This medicine is resistant to beta-lactamases, an enzyme bacteria produce to inactivate certain antibiotics, making it an ideal choice for treating various bacterial infections.

Encef 1000mg Injection is used to treat pneumonia (infection of the lungs), meningitis (infection of the brain and spinal cord), sepsis (life-threatening reaction to an infection), pyelonephritis (kidney infection), and gonorrhoea (sexually transmitted disease affecting the reproductive tract). This medication is also prescribed for surgical prophylaxis and bacterial infections in the ear, nose, abdomen, blood, bones, joints, skin and urinary tract.

Ceftriaxone (contained in Encef 1000mg Injection) is effective against gram-negative bacteria such as Serratia, Pseudomonas, most Enterobacteriaceae, Haemophilus influenzae, Neisseria gonorrhoeae and Borrelia burgdorferi. It can also be used against a few gram-positive bacteria.

How Encef 1000mg Injection works

Encef 1000mg Injection contains ceftriaxone, which works by inhibiting cell wall synthesis, effectively killing the bacteria causing the infection. Ceftriaxone is a bactericidal drug, which means it kills bacteria instead of suppressing their growth, which is what bacteriostatic drugs do.

Ceftriaxone is third-generation cephalosporin that is effective against gram-negative bacteria such as Serratia, Pseudomonas, most Enterobacteriaceae, Haemophilus influenzae, Neisseria gonorrhoeae and Borrelia burgdorferi; as well as a few gram-positive bacteria as well. A factor that makes this antibiotic highly effective is its impressive CNS penetration, which means this medicine can enter the nervous system and treat severe infections that affect the brain and spinal cord.

Cephalosporins such as ceftriaxone inhibit cell wall synthesis by blocking the production of mucopeptide, which is a polymer substance found inside bacterial cell walls. This medicine binds penicillin-binding proteins with the help of unique chemical structures called beta-lactam rings. This binding results in the inhibition of transpeptidation in peptidoglycan, a process crucial for forming cell walls in bacteria. Without the cell wall, the bacteria die.

Dosage

Encef 1000mg Injection is injected directly into a vein/muscle or given as a drip/cannula under the supervision of your doctor. This medicine is administered at evenly spaced intervals per your doctor's prescription. Do not stop taking this antibiotic before the prescribed dosage is finished, even if you feel better. Stopping the medicine too early can lead to a return of or worsening of the symptoms.

The total daily doses for children should not exceed 2 gm. For adults, however, up to 4 gm per day is permissible. Doses depend on the extent of the bacterial infection. For surgical prophylaxis, a single dose containing 1 gm is given intravenously about 1 hour before the surgery. This medicine is to be injected into your body by a healthcare professional, do not try to self-administer.

Safety Advice

Encef 1000mg Injection is contraindicated (unsafe) for people with anaemia, congestive heart failure, colitis, liver diseases or allergies to cephalosporins like ceftriaxone. It is also not recommended to use this medicine in case of neonatal hyperbilirubinemia. Always let your doctor know of any health conditions you might have.

sdsPregnancyCaution

Can I take Encef 1000mg Injection if I’m pregnant?

sdsBreastfeedingConsult doctor

Can I take Encef 1000mg Injection if I’m breastfeeding?

sdsAlcoholCaution

Is drinking alcohol while taking Encef 1000mg Injection safe?

sdsDrivingCaution

Can I drive after taking Encef 1000mg Injection?

Drug interactions

Drug-Food interaction

Intake of alcohol should be limited after receiving Encef 1000mg Injection to reduce the medicine’s side effects. Please consult your doctor for more information.

Drug-Disease interaction

Encef 1000mg Injection is contraindicated (unsafe) for people with anaemia, bladder cancer, congestive heart failure, colitis, liver diseases or allergies to cephalosporins like ceftriaxone. This antibiotic is not used in infants suffering from neonatal hyperbilirubinemia.

Drug-Drug interaction

If you are already taking Encef 1000mg Injection, it is not recommended to take the following medicines: antibiotics (chloramphenicol, rifampicin, gatifloxacin), fibrates (gemfibrozil), Insulin injection, antifungal drugs (ketoconazole) and Aloe Vera.

Drug-Drug Interactions Checker List:

Chloramphenicol Rifampicin Gatifloxacin Gemfibrozil Insulin Aloe Vera Ketoconazole

Frequently Asked Questions

Q. What is Encef 1000mg Injection’s content?

Encef 1000mg Injection contains ceftriaxone, a third-generation bactericidal cephalosporin. This antibiotic is used to treat infections of the lungs, skin, urinary tract and abdomen.

Q. What is the use of Encef 1000mg Injection?

Encef 1000mg Injection is used in the treatment of pneumonia, meningitis, pyelonephritis, and gonorrhoea. It is also prescribed for infections in the ear, nose, abdomen, skin and urinary tract.

Q: What are the side effects of Encef 1000mg Injection?

Side effects of Encef 1000mg Injection include nausea, vomiting, vaginal itching, rash and diarrhoea. You might experience slight redness and warmth in the area of injection.

Q. Is Ceftriaxone and Encef 1000mg Injection same?

Yes, Encef 1000mg Injection contains 1 gm of ceftriaxone, a cephalosporin. This antibiotic is used to treat severe infections of the abdomen, lungs, skin and urinary tract.

Q. How quickly doesEncef 1000mg Injection work?

Encef 1000mg Injection starts working in a few hours after being administered intravenously or intramuscularly. However, complete elimination of the infection might take a few days.

References

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