Duorandil 5mg Tablet

Duorandil 5mg Tablet is a medicine used to prevent and treat heart-related chest pain (angina). It is usually prescribed when other heart medicines are not suitable or have not worked. It reduces the risk of an angina attack by widening blood vessels and improving blood flow to the heart.

Duorandil 5mg Tablet is administered under the supervision of a healthcare professional and should not be self administered. Your doctor will decide the dose and how often you should take them. Your doctor is likely to prescribe you oral medicines after the treatment with this medicine. You can improve the health of your heart by making some lifestyle changes such as quitting smoking, cutting down on alcohol, eating well, taking exercising regularly and managing stress.

The most common side effect of this medicine is headache, especially during the first few days of treatment. You can reduce this by drinking plenty of fluids and avoiding alcohol, but it usually goes after a week. Other common side effects include ulcer, feeling dizzy or weak, nausea and vomiting, palpitation, and flushing (sense of warmth in the face, ears, neck and trunk). Talk to your doctor if these bother you or do not go away.

Duorandil 5mg Tablet is not suitable for some people. Tell your doctor if you have low blood pressure, a problem with fluid in your lungs or kidney problems. Also let your healthcare team know all other medications you are using as some may affect, or be affected by this medicine. You should not take any medicines for erectile dysfunction with this medicine. This medicine is not usually recommended during pregnancy or breastfeeding. Drinking alcohol can increase the blood pressure-lowering effect of Duorandil 5mg Tablet. Your doctor may ask you to avoid salt substitutes.

• Treatment of Angina (heart-related chest pain)

Treatment of Angina (heart-related chest pain)
Duorandil 5mg Tablet helps in prevention as well as treatment of angina. Angina is chest pain that is usually caused by the narrowing of the blood vessels which supply your heart. This means your heart does not get enough oxygen. Duorandil 5mg Tablet relaxes and widens the blood vessels so more blood (and oxygen) gets to your heart. This reduces the pain and discomfort that angina causes thereby improving your ability to exercise and go about your daily life more easily. This medicine needs to be taken regularly to be effective so keep taking it even if you are not having any angina symptoms.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nikoran

• Headache
• Ulcer
• Dizziness
• Weakness
• Nausea
• Vomiting
• Palpitations
• Flushing (sense of warmth in the face, ears, neck and trunk)

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Duorandil 5mg Tablet is a vasodilator. It works by reducing the workload of the heart. As a result, heart muscle does not need as much blood and oxygen supply. This reduces the frequency and severity of angina attacks.

• You must continue to take it as advised, usually for a long time.

• Duorandil 5mg Tablet may cause headaches. Drink plenty of water and take a suitable painkiller. Inform your doctor if it does not go away.

• Duorandil 5mg Tablet may cause dizziness or sleepiness. Do not drive or do anything which requires concentration until you know how it affects you.

• Do not consume alcohol while taking Duorandil 5mg Tablet as that may cause increased dizziness.

• Do not take medications like sildenafil or tadalafil (prescribed for erectile dysfunction) while on treatment with Duorandil 5mg Tablet as it may cause low blood pressure.

• Inform your doctor if you notice any bleeding from the anal passage, blood in vomit or black stools.

Opie LH, Horowitz JD. Nitrates and Newer Antianginals β-Blocking Agents. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 57.

Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 198.

National Health Service. Nicorandil; 2019. [Accessed 18 Jun. 2019] (online) Available from:

Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from: