Dobunes Lypho 250mg Injection

Dobunes Lypho 250mg Injection is a medicine used for short-term treatment of cardiac decompensation (low blood pressure due to poorly functioning heart) due to disease like heart failure, cardiogenic shock, or heart attack. It increases the blood pressure by increasing the pumping capacity of the heart.

Dobunes Lypho 250mg Injection is also used while performing stress echocardiography evaluation of the heart. It is administered under the supervision of a doctor as it requires continuous blood pressure monitoring. The dose has to be individually adjusted as per the patient's response to therapy. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection. Your doctor may advise for regular monitoring of blood pressure.

It may cause side effects like high blood pressure and insomnia (difficulty in sleeping). You must inform the doctor if you are suffering from any liver or kidney disease. Also, let your doctor know about all the other medications that you are using regularly.

• Heart failure
• Low blood pressure

Heart failure
Heart failure means your heart is weak and cannot pump enough blood to your lungs and the rest of your body. The most common symptoms are breathlessness, tiredness, and swelling in your legs, ankles, abdomen and other parts of your body. Dobunes Lypho 250mg Injection makes it easier for your heart to pump blood around your body and is therefore an effective treatment for heart failure.
This medicine will help relieve your symptoms, making you feel better and more energetic. You should make appropriate lifestyle changes (such as eating healthily and keeping active) to help this medicine be effective. Follow your doctor’s instructions carefully to get maximum benefit.

Low blood pressure
Dobunes Lypho 250mg Injection is used to normalise decreased blood pressure (hypotension) which may occur all of a sudden during an operation, severe infection (sepsis) or due to an emergency condition (cardiac arrest). This medicine helps to bring back the blood pressure within normal range and therefore prevents any sudden fall or even serious complications that might have otherwise followed due to low blood pressure.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dobutameg

• High blood pressure
• Insomnia (difficulty in sleeping)

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Dobunes Lypho 250mg Injection is a sympathomimetic agonist. It works by activating the receptors in the heart. This makes the heart pump blood with more strength and force and increases its pumping capacity in conditions such as heart failure.

• It is given into the vein as a drip by a healthcare professional.
• Your doctor may perform regular blood tests to monitor the level of sodium and potassium in the blood.
• Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Maron BA, Rocco TP. Pharmacotherapy of Congestive Heart Failure. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 804-805.

Katzung BG, Parmley WW. Drugs Used in Heart Failure. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 216-217.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 421.

Teerlink JR, Sliwa K, Opie LH. Heart Failure. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 177-81.

Dobutamine hydrochloride. Gloucester, UK: Hameln Pharmaceuticals Ltd.; 1994 [revised 08 Aug. 2018]. [Accessed 23 Jan. 2019] (online) Available from:

Dobutamine. Hameln, Germany: Siegfried Hameln GmbH; 2018. [Accessed 15 Mar. 2019] (online) Available from:

Dobutamine. Lake Forest, Illinois: Hospira, Inc.; 2016. [Accessed 15 Mar. 2019] (online) Available from:

Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Dobutamine. [Updated 2018 Dec 3]. [Accessed 19 Feb. 2020] (online) Available from:

Central Drugs Standard Control Organisation (CDSCO). Dobutamine. [Accessed 15 Mar. 2019] (online) Available from: