Difisal Plus 50mg/325mg Tablet

Difisal Plus 50mg/325mg Tablet is a pain relieving medicine. It is used to reduce pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve fever, muscle pain, back pain, toothache, or pain in the ear and throat.

Difisal Plus 50mg/325mg Tablet is generally given by a doctor or a nurse and should not be self- administered. You should use it regularly as advised by your doctor. Your doctor may change the dose and time between doses according to your pain level and your needs. Do not use more or use it for a longer duration than recommended by your doctor.

Some of the common side effects of this medicine include nausea, vomiting, stomach pain, loss of appetite, heartburn, and diarrhea. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help you with ways to reduce or prevent these side effects by prescribing an alternative medicine or adjusting the dose.

The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, liver, or have stomach ulcers. To make sure it is safe for you, let your doctor know about all the other medicines you are taking. Pregnant and breastfeeding mothers should first consult their doctors before using this medicine.

• Pain relief

Pain relief
Difisal Plus 50mg/325mg Tablet is a combination of medicines that is used for short-term relief of pain, inflammation and swelling. It inhibits release of those chemical messengers in the brain that tell us that we have pain. It effectively relieves back pain, earache, throat pain, toothache and pain due to arthritis too.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ayufen P

• Nausea
• Vomiting
• Stomach pain/epigastric pain
• Heartburn
• Diarrhea
• Loss of appetite

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Difisal Plus 50mg/325mg Tablet is a combination of two medicines: Diclofenac and Paracetamol. These medicines work by blocking the action of chemical messengers responsible for pain, fever and inflammation (redness and swelling).

• You have been prescribed this combination medicine for relieving pain and inflammation.
• It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
• Avoid consuming alcohol when taking Difisal Plus 50mg/325mg Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
• Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.

Diclofenac. Dublin 2, Republic of Ireland: Flynn Pharma Ltd.; 2017. [Accessed 22 Apr. 2019] (online) Available from:

Acetaminophen. San Diego, California: Cadence Pharmaceuticals, Inc; 1951 [revised Nov. 2010]. [Accessed 22 Apr. 2019] (online) Available from:

Drugs.com. Diclofenac. [Accessed 22 Apr. 2019] (online) Available from:

Medscape. Acetaminophen. [Accessed 22 Apr. 2019] (online) Available from: