Defryl 30mg Tablet
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Introduction To Defryl 30mg Tablet
Defryl 30mg Tablet belongs to a group of medicines known as corticosteroids. Its anti- inflammatory and immunosuppressive properties give it the ability to treat a wide range of conditions in children. It is also one of the primary medicines used for Duchenne muscular dystrophy in infants and children.
Give Defryl 30mg Tablet to your child orally, either before or after food. Giving it with food helps prevent the risk of developing a stomach upset. Always give the dose as prescribed by the doctor since that depends on the severity and type of infection, body weight, and age of your child. If your child gains or loses weight during treatment, make sure to let the doctor know. Never alter the dose by yourself as that may increase the risk of serious implications in your child. If your child vomits within 30 minutes of taking this medicine, help the child calm down and repeat the same dose, but skip it if it is already time for the next dose.
It is important to complete the full course of this medicine as stopping it abruptly may cause serious side effects. To stop this medicine, the doctor will gradually taper down the dose of this medicine to avoid withdrawal symptoms. Defryl 30mg Tablet can suppress your child's immune system, making your child more prone to infections. Your child may need frequent medical checkups and tests. Therefore, it is important to follow up with your child's doctor frequently during the treatment. The doctor may also advise vision and bone mineral density check for your child as Defryl 30mg Tablet can impact both of these.
This medicine may cause side effects like weight gain, increased appetite, upper respiratory tract infection, cough, abnormal hair growth, central obesity, fluid and electrolyte disturbance, and common cold symptoms. Reach out to your child's doctor if these side effects appear.
Let your child's doctor know if your child is already taking medicines for any type of infection. Also, narrate your child's complete medical history, including heart, blood, skin, bone, and hormonal disorders or any prior episodes of allergy, eye disease, birth defects, lung anomaly, liver impairment, and kidney malfunction. This information is critical for dose alterations and in planning your child's overall treatment.
Uses of Defryl 30mg Tablet
- Treatment of Duchenne muscular dystrophy(DMD)
- Treatment of Inflammatory conditions
- Treatment of Autoimmune conditions
- Treatment of Cancer
Benefits of Defryl 30mg Tablet
Treatment of Duchenne muscular dystrophy(DMD)
Duchenne muscular dystrophy (DMD) is a type of muscular dystrophy,
characterized by muscle weakness and atrophy due to the effect of the body’s
immune system mechanisms. Defryl 30mg Tablet slows the progression of DMD. The exact
mechanism by which it acts is unclear, but it is thought to help mediate the
condition by suppressing the immune system. For DMD, Defryl 30mg Tablet is approved to
be used in children above 5 years of age.
Treatment of Inflammatory conditions
Defryl 30mg Tablet gives relief in inflammatory conditions that affect muscles and
joints such as arthritis and ankylosing spondylitis. It also helps manage
other inflammatory conditions such as asthma, inflammatory bowel disease,
uveitis, ulcerative colitis, and allergies. It works by blocking certain
chemicals that cause pain and swelling.
Treatment of Autoimmune conditions
Defryl 30mg Tablet gives relief in autoimmune conditions like psoriasis, rheumatoid
arthritis, eczema, atopic dermatitis, etc. It works by lowering your immune
system’s response to these conditions thereby reducing symptoms such as
swelling, pain, itching, and other allergic-type reactions.
Treatment of Cancer
Defryl 30mg Tablet helps in the treatment of a variety of cancers, such as leukemia,
lymphoma, and multiple myeloma. It works by suppressing the immune system
thereby reducing inflammation around the site of cancer. It is used
specifically to decrease swelling (edema), associated with tumors of the spine
and brain. Moreover, it helps to treat or prevent allergic reactions in cancer
patients.
Side effects of Defryl 30mg Tablet
Defryl 30mg Tablet does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Flezanix
- Common cold
- Increased appetite
- Weight gain
- Frequent urge to urinate
- Cushing syndrome
- Cough
- Abnormal hair growth
- Upper respiratory tract infection
- Obesity
- Nasopharyngitis (inflammation of the throat and nasal passages)
How to use Defryl 30mg Tablet
Take this medicine in the dose and duration as advised by your doctor. Check
the label for directions before use. Measure it with a measuring cup and take
it by mouth. Shake well before use. Defryl 30mg Tablet may be taken with or without
food, but it is better to take it at a fixed time.
Avoid Defryl 30mg Tablet with salad and vegetable diet.
How Defryl 30mg Tablet works
Defryl 30mg Tablet is a corticosteroid medicine. It acts like the body’s natural anti- inflammatory hormones called glucocorticoids. Defryl 30mg Tablet decreases the formation of chemical substances like prostaglandins, leukotrienes, and interleukins that are involved in inflammation, allergy, and cell multiplication. It also suppresses the immune system and stops the immune mechanisms from causing any self-damage to the body.
Quick tips
- Prefer giving Defryl 30mg Tablet with food as an empty stomach can trigger acidity and gastric reflux.
- Avoid giving antacids along with Defryl 30mg Tablet. If both need to be given, leave a gap of at least 2 hours between administration of Defryl 30mg Tablet and antacids.
- Do not give it more often or for longer than advised by your doctor.
- Defryl 30mg Tablet can make it harder for your child to fight off infections. Notify your doctor if you notice any signs of infection such as a fever or sore throat.
- Do not stop the medicine abruptly. Seek the doctor’s guidance to taper the dose gradually as sudden withdrawal may result in a steroid withdrawal syndrome.
Safety Advice
KidneySAFE IF PRESCRIBED
Can I take Defryl 30mg Tablet if I have/had kidney diseases?
Defryl 30mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Defryl 30mg Tablet is recommended. Dose alterations may be required in severe kidney disease. Discuss with your child’s doctor thoroughly before giving Defryl 30mg Tablet to your child.
LiverCAUTION
Can I take Defryl 30mg Tablet if I have/had liver diseases?
Defryl 30mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Defryl 30mg Tablet may be needed. Please consult your doctor.
Frequently Asked Questions
Q. Is Defryl 30mg Tablet a steroid?
Yes, Defryl 30mg Tablet is a steroid medicine also known as glucocorticoids which occur naturally in the body. These glucocorticoids help to maintain health and wellbeing. Defryl 30mg Tablet increases the corticosteroids levels in the body which helps in treating various illnesses involving inflammation (redness, tenderness, heat and swelling).
Q. In what conditions should I avoid giving Defryl 30mg Tablet to my child?
Avoid giving Defryl 30mg Tablet to your child if they have conditions like cardiac disease or congestive heart failure (except in the presence of active rheumatic carditis), hypertension, thromboembolic disorders, or diabetes mellitus. Defryl 30mg Tablet should also be avoided if your child has a family history of active TB, active herpes infection, osteoporosis, myasthenia gravis, or renal insufficiency.
Q. What do I need to know about Defryl 30mg Tablet and my child’s immunizations?
For certain vaccines (live or live-attenuated vaccines), your child will need to wait 4 to 6 weeks before starting Defryl 30mg Tablet. Hence, your child needs to receive all immunizations according to immunization guidelines before they start taking Defryl 30mg Tablet.
Q. How can I store Defryl 30mg Tablet at home?
Keep the medicine in a cool dry place out of the reach of children and pets. This will help avoid any accidental intake.
Q. My child is suffering from a seizure disorder. Is it safe to give Defryl 30mg Tablet to my child?
Ans: Prolonged intake of Defryl 30mg Tablet can lead to mental illness as well as a seizure disorder. Therefore, any child who is already suffering from seizure disorder should not take Defryl 30mg Tablet.
References
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Written By:
Dr Advikka Ridhy
MBBS
RMO, Aster MIMS
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