Comvac 4 HB Injection

Comvac 4 HB Injection is a combination medicine used to prevent diphtheria, tetanus, pertussis and chronic hepatitis B virus (HBV) infection. It helps in developing immunity by initiating a mild infection. It helps the immune system to produce antibodies (proteins) to protect against any future infections.

Comvac 4 HB Injection should be injected by a doctor or healthcare professional. It is given via muscle in the anterolateral region of the thigh of infants and young children. You should not take it if you have any known allergy from this injection. Do not skip any doses and follow your doctor's instructions carefully to get maximum benefit.

The most common side effects include redness at the injection site, tenderness, irritability, vomiting, loss of appetite and fever. If any of these side effects or any other symptoms which you think are because of this medicine persist for a longer duration, please inform your doctor.

• Prevention of Diphtheria
• Prevention of Tetanus
• Prevention of Pertussis
• Prevention of Chronic hepatitis B virus (HBV) infection

Prevention of Diphtheria
Diphtheria is a bacterial infection that causes pain and swelling in the throat. This might cause difficulty in breathing. It might also damage the heart, kidneys and nerves. Comvac 4 HB Injection gives protection against diphtheria. It is recommended to get your child vaccinated against diphtheria starting at 6 weeks through 6 years. It is advisable to consult your doctor for complete information regarding vaccination schedules.

Prevention of Tetanus
Tetanus is a serious bacterial infection that affects the nervous system and causes muscles throughout the body to become stiff and tighten. Comvac 4 HB Injection helps prevent tetanus infection. It helps the immune system to produce antibodies to fight against tetanus infection. However, it does not provide lifelong protection. Children need to get a booster shot at 11 or 12 years of age. Adults need a booster shot every 10 years after that. It is advisable to consult your doctor for complete information regarding vaccination schedules.

Prevention of Pertussis
Pertussis (often called whooping cough) is an infection of the airways that can occur at any age but mostly affects infants and young children. The infection causes uncontrollable coughing that can make it difficult to breathe. Comvac 4 HB Injection gives protection from pertussis. Infants and children need a dose of the vaccine starting at 2 months through 6 years. However, it is advisable to consult your doctor for complete information regarding vaccination schedules.

Prevention of Chronic hepatitis B virus (HBV) infection
Hepatitis B is an infection of the liver caused by the Hepatitis B virus (HBV). When the infection moves into a long-lasting stage, it is called chronic hepatitis B virus infection. It can spread from person to person through blood, semen or other body fluids. Hepatitis B can cause mild illness lasting a few weeks, or it can lead to a serious, lifelong illness. Comvac 4 HB Injection is given to prevent hepatitis B infection. It is recommended for all infants and children of 6 weeks through 6 years of age. Hoever, it is advisable to consult your doctor for complete information regarding vaccination schedules.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Comvac 4 HB

• Injection site reactions (pain, swelling, redness)
• Headache
• Body ache
• Muscle weakness
• Tiredness
• Joint pain
• Feeling of discomfort

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Comvac 4 HB Injection is a combination of four medicines. Diphtheria Toxoid, Tetanus Toxoid, Pertussis Toxoid, and Hepatitis B Vaccine (rDNA) are vaccines (inactivated microorganisms) that are formulated together to develop immunity by initiating a mild infection. This type of infection does not cause illness but stimulates the body's immune system to produce antibodies (proteins) to protect against any future infections. Aluminium Hydroxide is an adjuvant that helps to potentiate the action of the vaccine in the body by increasing its uptake. This is how it works to prevent various viral and bacterial infections.

COMVAC 4-Hb. Bharat Biotech. [Accessed 12 Sep. 2019] (online) Available from: