Comig 500 Tablet

Comig 500 Tablet is a combination of domperidone and naproxen prescribed to treat migraine attacks (acute management of migraines). This medication works by blocking certain pain-causing chemical substances and preventing the stimulation of the brain's vomiting centre. It reduces symptoms like nausea, vomiting and headaches.

Comig 500 Tablet should be taken as advised by your doctor. The dose of the medication may be adjusted depending on the severity of your symptoms. It is best to take this medicine with your meal to prevent stomach upset. To avoid adverse effects, take it as per your doctor’s prescription.

The common side effects of Comig 500 Tablet include dry mouth, dizziness, cold symptoms, ringing in ears, headache and flatulence (gas). They typically last for a short period and should not be of any concern. Contact your healthcare provider if they persist or worsen.

Comig 500 Tablet might be contraindicated (unsafe) for people with vertigo, peptic and gastric ulcers, kidney impairment, severe liver disease, congestive heart failure or allergies to either domperidone or naproxen. Always let your doctor know of any health conditions you might have. This combination drug is generally considered safe for most people.

Comig 500 Tablet is used for the acute management of migraines as it treats migraine attacks (severe headaches with nausea, vomiting and sensitivity to light). This medication works by blocking pain-causing chemical substances and preventing the stimulation of the brain's vomiting centre. This medication may also be prescribed for various medical conditions that cause pain, nausea, and vomiting.

Comig 500 Tablet comprises two active medicines: domperidone and naproxen. Domperidone is an anti-sickness medication that treats vestibular disorders, vomiting and nausea. Naproxen is a nonsteroidal anti-inflammatory drug that relieves pain.

Comig 500 Tablet contains domperidone and naproxen; it works by blocking certain enzymes and preventing the stimulation of the brain's vomiting centre. It reduces symptoms like nausea, vomiting and pain associated with migraine headaches.

Domperidone can be classed as an anti-sickness medication. It belongs to a group of drugs named dopamine-2 receptor antagonists. This inhibition of dopamine receptors in our body allows it to act as a prokinetic (medicines that increase the speed of food passage in the digestive system) and an antiemetic agent (medicines that reduce nausea and vomiting).

Naproxen is a non-steroidal anti-inflammatory drug that reduces pain and inflammation. It works by inhibiting enzymes called COX-1 and COX-2. This lowers the synthesis of prostaglandins (hormone-like chemicals responsible for pain and inflammation). Its analgesic properties are attributed to its ability to lower levels of prostaglandin in the tissue and blood.

• Domperidone (www.nhs.uk)
• Naproxen (medlineplus.gov)
• Naproxen (www.ncbi.nlm.nih.gov)