Combisun Tablet

Combisun Tablet is a combination of ibuprofen and paracetamol. It is used to treat fever and pain in infants and children. It works by reducing inflammation in the tissue and blocking pain signals in the nervous system. This oral medicine alleviates mild-moderate pain and lowers body temperature. This combination is also prescribed to treat inflammations and (rarely) juvenile arthritis.

Combisun Tablet should be given to your child as advised by your doctor. The dosage may be adjusted depending on the level of pain.. It is best to drink this oral medicine after having food to avoid stomach discomfort. To prevent adverse effects, take it as per your doctor’s prescription.

Side effects of Combisun Tablet include stomach pain, nausea, vomiting, diarrhoea, heartburn, drowsiness and loss of appetite. They typically last for a short period and should not be of any concern.

Combisun Tablet is contraindicated (unsafe) for children with a history of stomach ulcers, liver diseases or allergies to either ibuprofen or paracetamol. Always let your doctor know of any health conditions your child might have. Generally, this combination drug is considered safe for most people.

Combisun Tablet is a combination pain medication used to treat mild-moderate pain and fever in children. It also helps alleviate all kinds of general discomfort, including dental pain, ear pain and headaches. This medication is also prescribed in cases of joint pain and disorders like arthritis.

Combisun Tablet consists of 2 active ingredients: ibuprofen, a non-selective non-steroidal anti-inflammatory drug (NSAID) and paracetamol, a non-narcotic analgesic-antipyretic agent.

They act as analgesics (pain killers), antipyretics (medicines that lower body temperature) and anti-inflammatory drugs by inhibiting pain signals in our nervous system and reducing inflammation in our tissue.

Adults can take this medication even though it is indicated for children and infants. Adults of any age can use this combination of ibuprofen and paracetamol to reduce a variety of symptoms like joint pain, migraines, menstrual cramps, dental/ear pain and muscle strain.

Combisun Tablet contains ibuprofen and paracetamol, it works by blocking COX enzymes in our body that produce a chemical substance responsible for pain, fever and inflammation.

Ibuprofen is a non-steroidal anti-inflammatory (NSAID) medicine which, as the name suggests, means it is not a steroid, and it reduces inflammations (and the pain that follows)

It does three things in our body: it lowers pain, reduces inflammation and stops your temperature from increasing. It targets natural chemicals called cyclo-oxygenase enzymes or COX enzymes in short. Aceclofenac blocks the effect of these COX enzymes and prevents them from producing a substance called prostaglandins. Thus the inhibition of cyclooxygenase-mediated prostaglandins occurs.

Prostaglandins are chemical substances related to pain. They are made at the site of injury or inflammation. When they are blocked or inhibited by medicines like aceclofenac or paracetamol, the pain sensation is reduced.

Paracetamol, also known as acetaminophen, is a non-narcotic analgesic-antipyretic agent. It means it reduces both pain and fever. It is believed to work by preventing the production of prostaglandins. When compared to Ibuprofen, however, it is a weak anti-inflammatory agent.

Combined, ibuprofen and paracetamol in Combisun Tablet inhibit all cyclooxygenase-mediated prostaglandins allowing them to offer a superior pain-relieving and antipyretic effect.

• A clinical and safety review of paracetamol and ibuprofen in children (ncbi.nlm.nih.gov)
• Medicines for babies and children (nhs.uk)
• Philip Anderson - Handbook of Clinical Drug Data-McGraw-Hill Medical (2001)