Colifine 10mg/325mg/250mg Tablet

Colifine 10mg/325mg/250mg Tablet is a combination medicine used in the treatment of abdominal cramps. It works effectively to reduce abdominal pain and cramps by relaxing the muscles of the stomach and gut. It also blocks certain chemical messengers that cause pain and fever.

Colifine 10mg/325mg/250mg Tablet is taken with food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are nausea, vomiting, heartburn, loss of appetite, indigestion, dryness in mouth, blurred vision, weakness, diarrhea, and nervousness. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.

• Abdominal cramp

Abdominal cramp
Colifine 10mg/325mg/250mg Tablet effectively relieves sudden muscle spasms or contractions in the stomach and intestine (gut), thereby relaxing the muscles and improving movement of food. This helps to treat abdominal cramps, as well as abdominal pain (or stomach pain), bloating and discomfort. Take a fiber-rich diet, avoid oily or spicy food and drink plenty of fluids while taking it to make sure you stay hydrated. Eventually, it will help you to go about your daily activities more easily and have a better, more active, quality of life.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Mefross

• Nausea
• Vomiting
• Indigestion
• Diarrhea
• Loss of appetite
• Sleepiness
• Weakness
• Nervousness
• Dryness in mouth
• Blurred vision
• Heartburn

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Colifine 10mg/325mg/250mg Tablet is to be taken with food.

Colifine 10mg/325mg/250mg Tablet is a combination of three medicines: Dicyclomine, Paracetamol and Mefenamic Acid which relieve abdominal pain. Dicyclomine is an anticholinergic. It works by relaxing the muscles in your stomach and gut (intestine). It stops sudden muscle contractions (spasms). By doing this, it relieves cramps, pain, bloating, and discomfort. Paracetamol is an antipyretic (fever reducer) and Mefenamic Acid acid is a non-steroidal anti-inflammatory drug (NSAID). They work by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).

• You have been prescribed Colifine 10mg/325mg/250mg Tablet to relieve abdominal pain.
• Stick to simple meals and avoid spicy rich food in order to avoid feeling sick (nausea).
• If you get diarrhea while taking this medicine, consult your doctor immediately.
• Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
• Do not take indigestion remedies (antacids) within two hours of taking Colifine 10mg/325mg/250mg Tablet.
• If you develop any new symptoms, or if your symptoms get worse, make an appointment to see your doctor for further advice.

NHS. Paracetamol for adults. [Accessed 14 Feb. 2019] (online) Available from:

Dicyclomine. Birmingham, Alabama: Axcan Scandipharm Inc.; 2005. [Accessed 15 Apr. 2019] (online) Available from:

Paracetamol. Barnstaple, Devon: Actavis UK Limited; 1980 [revised 23 Dec. 2016]. [Accessed 15 Apr. 2019] (online) Available from:

Mefenamic Acid. 2008 [revised Mar. 2007]. [Accessed 15 Apr. 2019] (online) Available from: