Cobus G 300mg/750mcg Tablet

Cobus G 300mg/750mcg Tablet is a combination medicine used for the treatment of neuropathic pain. This medicine decreases pain by modulating calcium channel activity of the nerve cells.

Cobus G 300mg/750mcg Tablet is taken by mouth with or without food, preferably at bedtime. It is advised to take medicine at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor.

Some common side effects of this medicine are nausea, peripheral edema, ataxia, blurred vision, fever and nystagmus (involuntary eye movement). It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.

Before taking the medicine you should tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. It can usually be mixed safely with other medicines but some drugs (including antacids and alcohol) do affect the way it works and can increase the chance of side effects.

• Treatment of Neuropathic pain

Treatment of Neuropathic pain
Cobus G 300mg/750mcg Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It is thought to work by interfering with pain signals that travel through the damaged nerves and the brain. Using this medicine regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to use it regularly even if you feel it is not doing any good. Once your symptoms have gone you should still keep using the medicine until your doctor advises you to stop.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Gabamune

• Dizziness
• Sleepiness
• Tiredness
• Uncoordinated body movements

Take this medicine in the dose and duration as advised by your doctor. Cobus G 300mg/750mcg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Cobus G 300mg/750mcg Tablet is a combination of two medicines: Gabapentin and Methylcobalamin. Gabapentin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).

• You have been prescribed Cobus G 300mg/750mcg Tablet for treating and preventing nerve pain.
• Its side effects are usually mild and temporary.
• It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
• To lower the chances of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
• Avoid consuming alcohol when taking Cobus G 300mg/750mcg Tablet, as it may cause excessive sleepiness.
• Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression or suicidal thoughts or behavior.
• Do not stop taking the medication suddenly without talking to your doctor.

Stahl SM, editor. Gabapentin. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 275-77.

McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 599.

Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 410.

Combs Jr. GF, McClung JP. The Vitamins: Fundamental Aspects in Nutrition and Health. 5th ed. Westborough, MA: Academic Press; 2017.

PubChem. Methylcobalamin hydrate. [Accessed 22 Apr. 2019] (online) Available from: