Clozine Plus 100 mg/2 mg Tablet

Clozine Plus 100 mg/2 mg Tablet is a combination medicine used in the treatment of schizophrenia (a mental disorder in which a person develops unreal thoughts and behavior). It alters the thoughts and elevates the mood, improving the person’s ability to think, feel and behave.

Clozine Plus 100 mg/2 mg Tablet may be taken with or without food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include nausea, constipation, dryness in mouth, sedation, abnormal heart rhythm, urinary retention, blurred vision, and nervousness. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you.

Before taking it, inform your doctor if you are suffering from thyroid or kidney problems, epilepsy, Parkinson's disease, glaucoma, or any heart problems. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.

• Schizophrenia

Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Clozine Plus 100 mg/2 mg Tablet helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life. Do not stop taking it unless advised by the doctor. It can take several weeks for your symptoms to improve; so keep using the medicine even if you do not think it is working.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Trixytin CP

• Nausea
• Constipation
• Sedation
• Weight gain
• Orthostatic hypotension (sudden lowering of blood pressure on standing)
• Urinary retention
• Increased prolactin level in blood
• Dizziness
• Blurred vision
• Dryness in mouth
• Nervousness

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clozine Plus 100 mg/2 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Clozine Plus 100 mg/2 mg Tablet is a combination of two medicines: Chlorpromazine and Trihexyphenidyl. Chlorpromazine is a typical antipsychotic. It works by blocking the action of a chemical messenger (dopamine) in the brain that affects thoughts and mood. However, it may cause side effects such as involuntary movements (shaking of hands, muscle spasms). Trihexyphenidyl is added to treat and prevent these side effects.

• Clozine Plus 100 mg/2 mg Tablet is a combination medicine that helps treat schizophrenia.
• Trihexyphenidyl controls drug induced abnormal movements.
• Be cautious while driving or doing anything that requires concentration as Clozine Plus 100 mg/2 mg Tablet can cause dizziness and sleepiness.
• Avoid consuming alcohol while taking this medication as it may lower its efficacy.
• It can cause dry mouth. Maintain good oral hygiene,drink water, chew sugarless gum, or suck on hard candy for the dry mouth.
• It can make you more sensitive to changes in temperature. Drink plenty of liquids and dress appropriately.
• To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
• Inform your doctor if you have glaucoma or trouble passing urine.
• Do not stop taking Clozine Plus 100 mg/2 mg Tablet without talking to your doctor first as it may cause worsening of symptoms.

Chlorpromazine. Beverley, Hull: Dr. Reddy's Laboratories (UK) Ltd.; 2005 [revised 14 Dec. 2016]. [Accessed 23 Apr. 2019] (online) Available from:

Trihexyphnidyl. Huddersfield, West Yorkshire: Genus Pharmaceuticals; 2011 [revised 18 Dec. 2018]. [Accessed 23 Apr. 2019] (online) Available from:

Drugs.com. Chlorpromazine. [Accessed 23 Apr. 2019] (online) Available from:

Drugs.com. Trihexyphenidyl. [Accessed 23 Apr. 2019] (online) Available from: