Closis Plus Tablet

Closis Plus Tablet is a prescription medicine used to treat anxiety disorder. It calms the brain by decreasing the abnormal and excessive activity of the nerve cells. It blocks the action of certain chemical messengers on the heart and blood vessels. This reduces heart rate and blood pressure.

Closis Plus Tablet should be taken on an empty stomach. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as it has high habit-forming potential. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly as it may cause withdrawal symptoms. Avoid consuming alcohol while taking this medicine as this may reduce its effectiveness.

Some common side effects of this medicine include confusion, memory impairment, slow heart rate, tiredness, and nightmare. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you develop any unusual changes in mood or depression as this medicine may cause suicidal thoughts.

Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

• Treatment of Anxiety disorder

Treatment of Anxiety disorder
Closis Plus Tablet stops your brain from releasing the chemicals that make you feel anxious so it can reduce the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, feeling irritable and sleep problems that often come with Generalised Anxiety Disorder. Closis Plus Tablet will therefore help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping suddenly can cause serious problems.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Clonax-Forte

• Confusion
• Memory impairment
• Drowsiness
• Slow heart rate
• Tiredness
• Uncoordinated body movements
• Nightmares
• Cold extremities

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Closis Plus Tablet is to be taken empty stomach.

Closis Plus Tablet is a combination of two medicines: Clonazepam and Propranolol. Clonazepam is a benzodiazepine. It works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in brain. Propranolol is a beta blocker which blocks the action of certain chemical messengers on the heart and blood vessels. This reduces heart rate, blood pressure, and strain on the heart.

• Closis Plus Tablet is used for the treatment of anxiety.
• It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
• Do not stop taking Closis Plus Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
• Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
• If you are due to have an operation or dental treatment, it is important to tell the person carrying out the treatment that you are taking.
• Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
• Closis Plus Tablet is used for the treatment of anxiety.
• It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
• It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
• Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
• If you are due to have an operation or dental treatment, it is important to tell the person carrying out the treatment that you are taking.
• Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.

Clonazepam. Boucherville, Québec: Sandoz Canada Inc.; 2018. [Accessed 22 Apr. 2019] (online) Available from:

Propranolol. Barnstaple, UK: Actavis; 2018. [Accessed 22 Apr. 2019] (online) Available from:

Clonazepam. Boucherville, Québec: Sandoz Canada Inc.; 2018. [Accessed 22 Apr. 2019] (online) Available from:

Drugs.com. Propranolol. [Accessed 22 Apr. 2019] (online) Available from: