Clistar-M Tablet

Clistar-M Tablet is used to treat irritable bowel syndrome (symptoms include abdominal pain, cramping, bloating, and diarrhea or constipation). It prevents the sudden spasm of muscles to relieve stomach pain and cramps. It also promotes easy passage of gas to reduce stomach discomfort.

Clistar-M Tablet is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are fatigue, confusion, uncoordinated body movements, skin rash, and slurred speech. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.

Lifestyle modifications like having fiber-rich diet, avoiding foods that trigger your symptoms, increasing fluid intake and regular exercise can help you to get better results. Before taking it, you should tell your doctor if you have any kidney or liver diseases. You should also tell your doctor if you are pregnant, planning pregnancy or breastfeeding.

• Irritable bowel syndrome

Irritable bowel syndrome
Irritable bowel syndrome is a chronic (long-term) inflammatory disease of the large intestine (colon) that usually needs long term management. This can lead to bleeding, frequent diarrhea, bloating, flatulence, cramps and stomach pain. Clistar-M Tablet relaxes the muscles in your stomach and gut (intestine) and relieves these symptoms effectively. Usually, it is used along with other medicines for management of your condition.
Continue taking it for as long as the doctor may advise you to. You need to take this medicine regularly to get the most out of it. Take a fiber-rich diet, avoid oily or spicy food and drink plenty of fluids while taking it to make sure you stay hydrated.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Benizep

• Sleepiness
• Drowsiness
• Fatigue
• Confusion
• Uncoordinated body movements
• Abnormality of voluntary movements
• Skin rash
• Slurred speech

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clistar-M Tablet is to be taken empty stomach.

Clistar-M Tablet is a combination of two medicines: Mebeverine and Chlordiazepoxide. Mebeverine is an antispasmodic medicine which relaxes the muscles of the intestine and relieves spasm. Chlordiazepoxide is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.

• You have been prescribed Clistar-M Tablet for the treatment of pain and other discomfort associated with irritable bowel syndrome.
• Do not take Clistar-M Tablet at least 2 hours before or after taking other medicines as it may interact with other medicines.
• Inform your doctor if you have an enlarged prostate gland, glaucoma, or trouble passing urine.
• To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.

Mebeverine hydrochloride. Châtillon-sur-Chalaronne, France: Mylan Laboratories SAS; 2016. [Accessed 28 Mar. 2019] (online) Available from:

Drugs.com. Chlordiazepoxide Pregnancy and Breastfeeding Warnings. [Accessed 20 Mar. 2019] (online) Available from:

Mebeverine hydrochloride. Potters Bar, Hertfordshire: Mylan Products Ltd.; 2005 [revised 26 Aug. 2016]. [Accessed 28 Mar. 2019] (online) Available from:

Chlordiazepoxide hydrochloride. Ashford, Kent: Kent Pharmaceuticals Ltd.; 2003 [revised 16 Aug. 2018]. (online) Available from: