Celrixafor Injection

Celrixafor Injection is used in Autologous stem cell transplant. It is a procedure in which certain blood cells are removed from the body and then returned to the body after the chemotherapy and/or radiation in patients with certain cancers.

Celrixafor Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, diarrhea, and injection site reaction. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Before taking it, tell your doctor if you have abnormal levels of blood cells or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

• Autologous stem cell transplant

Autologous stem cell transplant
In an autologous transplant, your own blood-forming stem cells are collected. Celrixafor Injection removes the blood-producing cells from the bone marrow into the bloodstream. These cells can be collected and used for transplant. This medicine is given by a doctor or nurse. Follow your doctor’s instructions carefully to get the most benefit.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Stemfor

• Nausea
• Diarrhea
• Injection site reaction

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Celrixafor Injection is an hematopoeitic stem cell mobilizers. It works by causing certain blood cells to move from the bone marrow to the blood so that they can be removed for transplant.

• Celrixafor Injection is given as an injection under the skin under the supervision of a doctor.
• Do not skip any dose and complete the course as suggested by your doctor.
• Use an effective method of birth control to avoid pregnancy while taking this medication.
• Your doctor may get regular blood tests done to monitor your blood cell count and liver function.
• Inform your doctor if you experience rash, itching, swelling, hives, shortness of breath, fast heart beat and drop in blood pressure.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1129.

Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:

Plerixafor. Oxford, Oxfordshire: Genzyme Therapeutics; 2009 [revised 20 Dec. 2018]. [Accessed 26 Mar. 2019] (online) Available from:

Plerixafor. Haverhill, Suffolk: Genzyme Ltd.; 2009 [Accessed 26 Mar. 2019] (online) Available from: