Celofos 1gm Injection

Celofos 1gm Injection is used in the treatment of different kinds of cancers. It is given alone or in combination with other chemotherapy medicines, radiotherapy and surgery to treat cancer of blood, breast, lung, ovaries, pancreas, testes, and lymph nodes.

Celofos 1gm Injection is usually given as a slow infusion (drip) into a vein (intravenously) over several hours. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well.

The most common side effects of this medicine include nausea, vomiting, anemia (low number of red blood cells), hair loss, decreased white blood cells count. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped.

• Pancreatic cancer
• Ovarian cancer
• Breast cancer
• Non-small cell lung cancer
• Testicular cancer
• Blood cancer

Pancreatic cancer
Pancreas are very essential for digestion of whatever you eat and also for metabolism of blood sugar levels as they produce the body’s natural insulin. This medicine will help to control pancreatic cancer, and will relieve the symptoms such as, lack of appetite or unexplained weight loss. Celofos 1gm Injection helps to stop the action of those chemicals that aid in pancreatic cancer growth and spread. It will help you live a longer and healthier life.

Ovarian cancer
Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Celofos 1gm Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but has some side effects that may be bothersome. So, you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Breast cancer
Celofos 1gm Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy, to treat cancer in various parts of the body. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Celofos 1gm Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.

Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Celofos 1gm Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Testicular cancer
Testicular cancer is the cancer in the male organs called testicles, that make male hormones and sperm. The testicles are located inside a loose bag of skin (scrotum) underneath the penis. Celofos 1gm Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells in men. It is given as an injection by a doctor or nurse and should not be self-administered.

Blood cancer
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Celofos 1gm Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Fosfa

• Nausea
• Vomiting
• Anemia (low number of red blood cells)
• Hair loss
• Decreased white blood cell count
• Infection
• Blood in urine
• CNS toxicity

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Celofos 1gm Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

• Celofos 1gm Injection is used in combination with other chemotherapy medicines, radiotherapy and surgery to treat cancer of blood, breast, lung, ovaries, pancreas, testes, and lymph nodes.
• It is usually given as a slow infusion (drip) into a vein (intravenously) over several hours.
• Drink plenty of fluids while taking this medication to minimise damage to your bladder and kidneys.
• It may cause dizziness and sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
• Use effective measures to avoid pregnancy during treatment with this medicine and for at least 6 months after your last dose as it can be harmful to an unborn baby.
• Your doctor may have your blood tested regularly to monitor your kidney, liver function and levels of blood cells in your blood.

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1683-84.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 688-90.

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Drugs.com. Ifosfamide Pregnancy and Breastfeeding Warnings. [Accessed 26 Mar. 2019] (online) Available from:

Ifosfamide. Deerfield, Illinois: Baxter Healthcare Corporation. [Accessed 26 Mar. 2019] (online) Available from: