Brigrel Tablet

Brigrel Tablet belongs to a group of medicines called antiplatelet or blood thinners. It reduces the formation of harmful blood clots in blood vessels. This helps to prevent a heart attack or stroke in people with heart disease.

Brigrel Tablet is also used to treat people with a recent heart attack or severe heart-related chest pain (unstable angina), who have undergone stenting of the heart. It helps to prevent serious heart-related problems like having another heart attack, stroke, or formation of blood clots in stents in such people.

Your doctor will also prescribe aspirin, another antiplatelet medicine, along with this medicine. Brigrel Tablet may be taken with or without food and should be taken regularly at the same time each day. It is important to keep taking it even if you feel well. If you stop taking this medicine, it may increase your chances of having another heart attack or stroke.

The most common side effect seen with this medicine is bleeding. If you cut or injure yourself, it may take longer than usual for the bleeding to stop. Such episodes of bleeding are usually mild and resolve on their own. Some people may develop mild breathlessness after taking this medicine, however, this usually resolves on its own with continued treatment. Let your doctor know if bleeding persists or if the breathlessness worsens or does not go away.

Brigrel Tablet is not suitable for some people. Do not take it if you are bleeding from anywhere in the body such as a stomach ulcer or bleeding within the brain. It is also not recommended for people with liver diseases. Before using the medicine, inform your doctor if you have any such problems.

• Prevention of heart attack and stroke

Prevention of heart attack and stroke
Brigrel Tablet is an antiplatelet medicine or blood thinner. It prevents blood from clotting inside the veins and arteries. This helps the blood flow freely around your body thereby preventing a heart attack or stroke (or deep vein thrombosis or pulmonary embolism). Take this medicine regularly and make appropriate lifestyle changes to achieve maximum benefits. It is often prescribed along with a low dose of aspirin which also helps to prevent blood from clotting.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ticabest

• Bleeding
• Breathlessness

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Brigrel Tablet may be taken with or without food, but it is better to take it at a fixed time.

Brigrel Tablet is an antiplatelet medication. It works by preventing platelets from sticking together, thereby decreasing the formation of harmful blood clots. This lowers the chance of heart attack or stroke.

• For best results, take it at the same time every day.
• Brigrel Tablet increases your risk of bleeding. Be careful while shaving, using sharp objects, or cutting fingernails or toenails.
• Do not discontinue using the medicine without consulting your doctor as this may increase your chances of having another heart attack or stroke.
• If you are scheduled to undergo a surgery or dental treatment, you may be asked to stop taking Brigrel Tablet temporarily.
• You may experience shortness of breath in the initial weeks of therapy. Notify your doctor if it becomes worse or persists for long.

Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 871-72.

Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 351-52.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1359-60.

Ticagrelor. Luton, Bedfordshire: AstraZeneca UK Limited; 2010 [revised 15th Nov. 2018]. [Accessed 24 Jan. 2019] (online) Available from:

Ticagrelor. Wilmington, Delaware: AstraZeneca LP; 2015. [Accessed 20 Mar. 2019] (online) Available from:

Ticagrelor. Wilmington, Delaware: AstraZeneca LP; 2011 [revised Sep. 2015]. [Accessed 19 Mar. 2019] (online) Available from:

Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from: