Biopolio B1/3 Oral Vaccine

Biopolio B1/3 Oral Vaccine is an inactivated polio vaccine (IPV). It protects against the virus that causes polio. Polio is a crippling and potentially deadly infectious disease that causes paralysis (cannot move body parts).

Biopolio B1/3 Oral Vaccine is given by injection by a doctor or nurse. It is given as FIPV (Fractional IPV) as a part of the Universal Immunisation Programme in the country. Two fractional doses of IPV are given to children at 6 and 14 weeks of age.

Biopolio B1/3 Oral Vaccine may cause mild fever and soreness and redness at the site of the injection for several days. It may also cause vomiting and diarrhea in some children. They do not normally last very long. Consult your doctor if any of the side effects persist or worry you.

Before having the injection, you should tell your doctor if you have ever had an allergic reaction to a vaccine. Some other medicines may react with the polio vaccine so talk to your doctor about other medications you are taking.

• Prevention of Polio

Prevention of Polio
Polio is a crippling and potentially deadly infectious disease. Poliovirus spreads from person to person and can invade an infected person's brain and spinal cord, causing paralysis. The vaccine contains inactivated (killed) viruses of all three poliovirus types (I, II, and III). It works by helping the immune system to produce antibodies that prevent the spread of the virus to the brain and protect against paralysis. It is generally given as an injection by a doctor or nurse.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Biopolio

• Injection site reactions (pain, swelling, redness)
• Fever
• Vomiting
• Diarrhea

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Biopolio B1/3 Oral Vaccine contains inactivated (killed) viruses of all three poliovirus types (I, II & III). It works by provoking the the immune system to produce antibodies (proteins), without actually causing a disease. In the event of infection, these antibodies prevent the spread of the virus to the brain and protect against paralysis.

• Biopolio B1/3 Oral Vaccine is given for the prevention of polio disease.
• Ensure that you take further booster doses of polio vaccine after every 5 years for children and after 10 years for adults.
• Inform your doctor if you are suffering from a high fever or any acute illness.
• Let your doctor know if you are taking any other medications like immunosuppressants.
• Tell your doctor if you are pregnant, planning to get pregnant, or breastfeeding.

Sinha A, Singh S. Immunization and Immunodeficiency. In: Paul VK, Bagga A, editors. Ghai Essential Pediatrics. 8th ed. New Delhi: CBS Publisher's & Distributors Pvt Ltd.; 2013. pp. 191-93.

Mayo Clinic. Poliovirus Vaccine, Inactivated (Injection Route). [Accessed 04 Apr. 2019] (online) Available from:

Polio Vaccine. Brentford Middlesex: SmithKline Beecham Ltd.; 2004 [revised 26 Jan. 2017]. [Accessed 04 Apr. 2019] (online) Available from:

Drugs.com. Poliovirus vaccine, inactivated Pregnancy and Breastfeeding Warnings. [Accessed 04 Apr. 2019] (online) Available from:

Drugs.com. Poliovirus Vaccines use while Breastfeeding. [Accessed 04 Apr. 2019] (online) Available from:

Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from: