Azoth 50 Tablet

Azoth 50 Tablet belongs to a group of medicines called immunosuppressants. It is used with other medicines to prevent your body from rejecting an organ (such as a kidney, heart, or liver) after a transplant. It is also used in the treatment of rheumatoid arthritis.

Azoth 50 Tablet works by weakening the body's immune system, so it does not attack the new organ. The amount of medicine to be taken and how often you need to take it will depend on the type of transplant you have. Follow your doctor's instructions on this. You should take it along with food. Take the medicine regularly to get the most benefit and keep taking it even if you feel well. If you stop taking it, you may increase the chances of rejecting your transplanted organ.

It has many potential side effects. The most common are loss of appetite, nausea, and increased risk of bleeding. Because it suppresses your immune system, you may catch infections easily. There's also an increased risk of developing some cancers for this reason. You should ask your doctor about side effects that may need urgent medical attention.

Azoth 50 Tablet can cause birth defects and miscarriages so do not take it if you are pregnant, planning to become pregnant, or breastfeeding. You should talk to your doctor before taking this medicine if you have any signs of infection or if you have any unexpected bruising or bleeding. Your doctor also needs to know what other medicines you are taking as there are many which interact with this medicine and affect the way it works. You will have regular tests to check for any changes in the number of your blood cells.

• Prevention of organ rejection in transplant patients
• Treatment of Rheumatoid arthritis

Prevention of organ rejection in transplant patients
Azoth 50 Tablet is an immunosuppressive agent that lowers your immune response and reduces the chance of your body attacking the transplanted organ. Organ rejection happens when your immune system treats the new organ as an invader and attacks it. This medicine may be used in combination with other medicines to suppress the immune system and help your body accept the new organ.

Treatment of Rheumatoid arthritis
Azoth 50 Tablet works by blocking the action of some chemicals which cause inflammation. It can help reduce pain, stiffness, and swelling in your joints and slow down the progression of bone and joint damage. This will help you do normal daily activities more easily and thus improve your quality of life. This medicine should be taken at the same time each day to get maximum benefits. Keep taking it even if you feel well because it is preventing future harm as well as improving your symptoms.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zoprine

• Decreased white blood cell count
• Increased bleeding tendency
• Nausea
• Infection
• Loss of appetite

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Azoth 50 Tablet is to be taken with food.

Azoth 50 Tablet is an immunosuppressant. It reduces the action of body's own defense system (the immune system) and prevents rejection of the transplanted organ. It also blocks the action of certain chemical messengers that are responsible for inflammation, swelling, and redness associated with certain joint diseases.

• Your doctor has prescribed Azoth 50 Tablet to stop the body from rejecting a transplanted organ (e.g. kidney, heart or liver).

• Azoth 50 Tablet also relieves joint pain and inflammation in rheumatoid arthritis.

• You may have to take additional medications along with Azoth 50 Tablet for better relief of symptoms.

• Avoid contact with people who have cold, flu or other contagious illness. Notify your doctor if you have any signs of infection such as a fever or sore throat.

• Inform your doctor if you are pregnant or planning to conceive or breastfeeding.

Krensky AM, Bennett WM, Vincenti F. Immunosuppressants, Tolerogens, and Immunostimulants. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1013-14.

Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 629-30.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 113-15.

Azathioprine. Barnstaple, Devon: Actavis UK Limited; 2018. [Accessed 05 Feb. 2019] (online) Available from:

Azathioprine. San Diego, California: Prometheus Laboratories Inc.; 2014. [Accessed 06 Apr. 2019] (online) Available from:

Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:

Azathioprine. Dartford, UK: Ennogen Pharma Ltd.; 2009 [revised 29 Jun. 2016]. [Accessed 17 Jun. 2019] (online) Available from:

Oxford Radcliffe Hospitals: NHS Trust. Azathioprine - General Information; 2012. [Accessed 17 Jun. 2019]. (online) Available from: